| Title: | Experimental wood smoke exposure in humans |
| Author(s): | Sallsten G; Gustafson P; Johansson L; Johannesson S; Molnar P; Strandberg B; Tullin C; Barregard L; |
| Address: | "Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital and Academy, Goteborg University, Goteborg, Sweden. gerd.sallsten@amm.gu.se" |
| DOI: | 10.1080/08958370600822391 |
| ISSN/ISBN: | 1091-7691 (Electronic) 0895-8378 (Linking) |
| Abstract: | "Experimental studies are used to evaluate effects of human exposure to diesel exhaust and concentrated ambient particles. This article describes a system for studying exposure of humans to wood smoke. Wood smoke was generated using a wood stove placed outside an exposure chamber that can hold at least 10 subjects. A partial flow of the generated wood smoke from the stove was mixed with filtered indoor air. Personal and stationary measurements were performed of PM2.5 and PM1 mass concentrations and various volatile organic compounds (VOCs): 1,3-butadiene, benzene, and aldehydes. In addition, particulate matter (PM) mass, number concentrations, and size distributions of particles (0.007-6.7 microm), as well as nitrous oxides, CO2, and CO, were measured online. Filters were analyzed for trace elements and black smoke. Polycyclic aromatic compounds, toluene, and xylenes were determined in stationary samples. Results of the first experiment showed no differences between personal and stationary measurements for particles or VOCs. Consequently, stationary measurements can be used to predict personal exposure. All PM mass (about 250 microg/m3) was in the PM1 fraction. Subjective symptoms were generally weak, while clear objective signs were found, for example, in biomarkers of inflammation. With careful control of the combustion process, relatively constant mass and number concentrations were obtained over each exposure session. By varying the combustion and dilution of the wood smoke, different exposure scenarios can be achieved and thus, knowledge about which of the properties of particles and gaseous compounds are crucial for the effects" |
| Keywords: | "Air Pollutants/*adverse effects/analysis Air Pollution, Indoor *Atmosphere Exposure Chambers Humans Inhalation Exposure/*adverse effects Particle Size Smoke/*adverse effects Smoke Inhalation Injury/*chemically induced/physiopathology *Wood;" |
| Notes: | "MedlineSallsten, Gerd Gustafson, Pernilla Johansson, Linda Johannesson, Sandra Molnar, Peter Strandberg, Bo Tullin, Claes Barregard, Lars eng Research Support, Non-U.S. Gov't England 2006/07/26 Inhal Toxicol. 2006 Oct; 18(11):855-64. doi: 10.1080/08958370600822391" |
