| Title: | "Nicotine, aerosol particles, carbonyls and volatile organic compounds in tobacco- and menthol-flavored e-cigarettes" |
| Author(s): | Lee MS; LeBouf RF; Son YS; Koutrakis P; Christiani DC; |
| Address: | "Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard T. H. Chan School of Public Health, 665 Huntington Ave, Building I Room 1401, Boston, MA 02115, USA. Centers for Disease Control and Prevention (CDC), National Institute for Occupational Safety and Health (NIOSH), Respiratory Health Division, Field Studies Branch, Morgantown, WV, USA. Research Division for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Daejeon, South Korea. Exposure, Epidemiology and Risk Program, Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, USA. Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard T. H. Chan School of Public Health, 665 Huntington Ave, Building I Room 1401, Boston, MA 02115, USA. dchris@hsph.harvard.edu. Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA. dchris@hsph.harvard.edu" |
| DOI: | 10.1186/s12940-017-0249-x |
| ISSN/ISBN: | 1476-069X (Electronic) 1476-069X (Linking) |
| Abstract: | "BACKGROUND: We aimed to assess the content of electronic cigarette (EC) emissions for five groups of potentially toxic compounds that are known to be present in tobacco smoke: nicotine, particles, carbonyls, volatile organic compounds (VOCs), and trace elements by flavor and puffing time. METHODS: We used ECs containing a common nicotine strength (1.8%) and the most popular flavors, tobacco and menthol. An automatic multiple smoking machine was used to generate EC aerosols under controlled conditions. Using a dilution chamber, we targeted nicotine concentrations similar to that of exposure in a general indoor environment. The selected toxic compounds were extracted from EC aerosols into a solid or liquid phase and analyzed with chromatographic and spectroscopic methods. RESULTS: We found that EC aerosols contained toxic compounds including nicotine, fine and nanoparticles, carbonyls, and some toxic VOCs such as benzene and toluene. Higher mass and number concentrations of aerosol particles were generated from tobacco-flavored ECs than from menthol-flavored ECs. CONCLUSION: We found that diluted machine-generated EC aerosols contain some pollutants. These findings are limited by the small number of ECs tested and the conditions of testing. More comprehensive research on EC exposure extending to more brands and flavor compounds is warranted" |
| Keywords: | Aerosols Air Pollutants/*analysis *Electronic Nicotine Delivery Systems Elements Menthol Nanoparticles/analysis Nicotine/*analysis Particulate Matter/*analysis Tobacco Volatile Organic Compounds/*analysis Carbonyls Nicotine Particles VOCs in e-cigarette e; |
| Notes: | "MedlineLee, Mi-Sun LeBouf, Ryan F Son, Youn-Suk Koutrakis, Petros Christiani, David C eng P30 ES000002/ES/NIEHS NIH HHS/ Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. England 2017/04/30 Environ Health. 2017 Apr 27; 16(1):42. doi: 10.1186/s12940-017-0249-x" |
