| Title: | Chemical Emissions from Cured and Uncured 3D-Printed Ventilator Patient Circuit Medical Parts |
| Author(s): | Krechmer JE; Phillips B; Chaloux N; Shomberg R; Daube C; Manchanda G; Murray S; McCarthy A; Fonseca R; Thakkar J; Loose B; Herndon SC; Jayne JT; Worsnop DR; Canagaratna MR; |
| Address: | "Aerodyne Research, Inc., 45 Manning Road, Billerica, Massachusetts 01821, United States. Department of Ocean Engineering, The University of Rhode Island, 215 South Ferry Road, Narragansett, Rhode Island 02882, United States. Formlabs, Inc., 35 Medford Street, Somerville, Massachusetts 02143, United States. Computer Science Department, Brown University, Providence, Rhode Island 02903, United States. Department of Medicine, Brown University and Alpert Medical School, Providence, Rhode Island 02903, United States" |
| ISSN/ISBN: | 2470-1343 (Electronic) 2470-1343 (Linking) |
| Abstract: | "Medical shortages during the COVID-19 pandemic saw numerous efforts to 3D print personal protective equipment and treatment supplies. There is, however, little research on the potential biocompatibility of 3D-printed parts using typical polymeric resins as pertaining to volatile organic compounds (VOCs), which have specific relevance for respiratory circuit equipment. Here, we measured VOCs emitted from freshly printed stereolithography (SLA) replacement medical parts using proton transfer reaction mass spectrometry and infrared differential absorption spectroscopy, and particulates using a scanning mobility particle sizer. We observed emission factors for individual VOCs ranging from approximately 0.001 to approximately 10 ng cm(-3) min(-1). Emissions were heavily dependent on postprint curing and mildly dependent on the type of SLA resin. Curing reduced the emission of all observed chemicals, and no compounds exceeded the recommended dose of 360 mug/d. VOC emissions steadily decreased for all parts over time, with an average e-folding time scale (time to decrease to 1/e of the starting value) of 2.6 +/- 0.9 h" |
| Notes: | "PubMed-not-MEDLINEKrechmer, Jordan E Phillips, Brennan Chaloux, Nicholas Shomberg, Russell Daube, Conner Manchanda, Gaurav Murray, Sam McCarthy, Alex Fonseca, Rodrigo Thakkar, Jinen Loose, Brice Herndon, Scott C Jayne, John T Worsnop, Douglas R Canagaratna, Manjula R eng 2021/11/23 ACS Omega. 2021 Nov 8; 6(45):30726-30733. doi: 10.1021/acsomega.1c04695. eCollection 2021 Nov 16" |
