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Acta Pharm

Title:		"An improved procedure for synthesis of some new 1,3-diaryl-2-propen-1-ones using PEG-400 as a recyclable solvent and their antimicrobial evaluation"
Author(s):		Dawane BS; Konda SG; Shaikh BM; Bhosale RB;
Address:		"Organic Research Laboratory Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S) India. bhaskardawane@rediffmail.com"
Journal Title:		Acta Pharm
Year:		2009
Volume:		59
Issue:		4
Page Number:		473 - 482
DOI:		10.2478/v10007-009-0034-7
ISSN/ISBN:		1846-9558 (Electronic) 1330-0075 (Linking)
Abstract:		"A simple and convenient route is described for the synthesis of novel hetero 1,3-diaryl-2-propen-1-ones (chalcones) by using recyclable PEG-400 as an alternative reaction solvent. The reaction is clean with excellent yield, shorter reaction time and reduces the use of volatile organic compounds (VOCs). All the synthesized compounds were evaluated for their antimicrobial activities against several pathogenic representatives"
Keywords:		Anti-Infective Agents/chemical synthesis/pharmacology Bacteria/drug effects Chalcones/*chemical synthesis/*pharmacology Green Chemistry Technology/methods Polyethylene Glycols/chemistry;
Notes:		"MedlineDawane, Bhaskar S Konda, Shankaraiah G Shaikh, Baseer M Bhosale, Raghunath B eng Poland 2009/11/19 Acta Pharm. 2009 Dec; 59(4):473-82. doi: 10.2478/v10007-009-0034-7"