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Paediatr Respir Rev

Title:		Exhaled breath testing - A tool for the clinician and researcher
Author(s):		Davis MD; Fowler SJ; Montpetit AJ;
Address:		"Division of Pulmonary Medicine, Children's Hospital of Richmond at VCU, Hermes A. Kontos Medical Sciences Building - Room 215, 1217 E. Marshall Street, Richmond, VA 23298, USA. Electronic address: Michael.D.Davis@vcuhealth.org. Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester and Manchester University NHS Foundation Trust, Manchester, UK. Electronic address: Stephen.fowler@manchester.ac.uk. VCU Health, Department of Emergency Medicine, Adult Emergency Department, Richmond, VA, USA. Electronic address: Alison.montpetit@vcuhealth.org"
Journal Title:		Paediatr Respir Rev
Year:		2019
Volume:		20180517
Issue:
Page Number:		37 - 41
DOI:		10.1016/j.prrv.2018.05.002
ISSN/ISBN:		1526-0550 (Electronic) 1526-0542 (Linking)
Abstract:		"Exhaled breath is a robust matrix of biomarkers divided between three fractions - gaseous breath, volatile breath, and breath condensate. Breath is collected non-invasively through bags (for gaseous breath), cold condensation chambers (breath condensate), and adsorbent traps (volatile breath). Due to the incredibly dilute nature of breath matrices, breath biomarker analysis requires precise analytical techniques, highly sensitive technology and often challenges the limit of detection of even the most advanced assays. Interest and advances in breath collection, analysis, and use have increased in recent years largely due to advances in analytical technology. Approved and validated breath tests are available as tools for researchers and clinicians. Novel development is ongoing. This article reviews the current applications for exhaled breath biomarkers"
Keywords:		Biomarkers/*analysis Breath Tests/*methods Carbon Dioxide/analysis Carbon Monoxide/analysis Exhalation Humans Hydrogen/analysis Nitric Oxide/analysis Urea/analysis Volatile Organic Compounds/analysis Biomarkers Exhaled biomarkers Exhaled breath Exhaled br;
Notes:		"MedlineDavis, Michael D Fowler, Stephen J Montpetit, Alison J eng Review England 2018/06/21 Paediatr Respir Rev. 2019 Feb; 29:37-41. doi: 10.1016/j.prrv.2018.05.002. Epub 2018 May 17"