« Previous AbstractParasitism overrides herbivore identity allowing hyperparasitoids to locate their parasitoid host using herbivore-induced plant volatiles    Next AbstractSpecies-specific plant-soil feedbacks alter herbivore-induced gene expression and defense chemistry in Plantago lanceolata »

Sci Rep

Title:		A specialist herbivore pest adaptation to xenobiotics through up-regulation of multiple Cytochrome P450s
Author(s):		Zhu F; Moural TW; Nelson DR; Palli SR;
Address:		"Department of Entomology, University of Kentucky, Lexington, KY 40546, USA. Department of Entomology, Washington State University, Pullman, WA 99164, USA. Department of Chemistry, Washington State University, Pullman 99164, USA. Department of Microbiology, Immunology and Biochemistry, University of Tennessee, Memphis, TN 38163, USA"
Journal Title:		Sci Rep
Year:		2016
Volume:		20160210
Issue:
Page Number:		20421 -
DOI:		10.1038/srep20421
ISSN/ISBN:		2045-2322 (Electronic) 2045-2322 (Linking)
Abstract:		"The adaptation of herbivorous insects to their host plants is hypothesized to be intimately associated with their ubiquitous development of resistance to synthetic pesticides. However, not much is known about the mechanisms underlying the relationship between detoxification of plant toxins and synthetic pesticides. To address this knowledge gap, we used specialist pest Colorado potato beetle (CPB) and its host plant, potato, as a model system. Next-generation sequencing (454 pyrosequencing) was performed to reveal the CPB transcriptome. Differential expression patterns of cytochrome P450 complement (CYPome) were analyzed between the susceptible (S) and imidacloprid resistant (R) beetles. We also evaluated the global transcriptome repertoire of CPB CYPome in response to the challenge by potato leaf allelochemicals and imidacloprid. The results showed that more than half (51.2%) of the CBP cytochrome P450 monooxygenases (P450s) that are up-regulated in the R strain are also induced by both host plant toxins and pesticide in a tissue-specific manner. These data suggest that xenobiotic adaptation in this specialist herbivore is through up-regulation of multiple P450s that are potentially involved in detoxifying both pesticide and plant allelochemicals"
Keywords:		"Adaptation, Physiological/*drug effects/genetics Animals Coleoptera/*physiology Cytochrome P-450 Enzyme System/classification/*genetics Gene Expression Profiling Gene Expression Regulation, Plant/*drug effects Herbivory/*drug effects/genetics Phylogeny Re;"
Notes:		"MedlineZhu, Fang Moural, Timothy W Nelson, David R Palli, Subba R eng Research Support, U.S. Gov't, Non-P.H.S. England 2016/02/11 Sci Rep. 2016 Feb 10; 6:20421. doi: 10.1038/srep20421"