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Trends Biochem Sci


Title:Structural aspects of sexual attraction and chemical communication in insects
Author(s):Tegoni M; Campanacci V; Cambillau C;
Address:"Architecture et Fonction des Macromolecules Biologiques, UMR 6098 CNRS and Universites Aix-Marseille I & II, 31 Ch. Joseph Aiguier, 13402 Marseille Cedex 20, France"
Journal Title:Trends Biochem Sci
Year:2004
Volume:29
Issue:5
Page Number:257 - 264
DOI: 10.1016/j.tibs.2004.03.003
ISSN/ISBN:0968-0004 (Print) 0968-0004 (Linking)
Abstract:"In the animal kingdom, the relationship between individuals and the environment is often modulated by chemical communication. In the olfaction of insects, small antennary proteins--such as odorant- and pheromone-binding proteins (OBPs and PBPs, respectively) and chemosensory proteins (CSP)--have been proposed to carry their ligand from the air-fluid interface to the olfactory receptors. Binding experiments and recent structural studies of three PBPs, an OBP and a CSP have illustrated their versatility and ability to accommodate ligands of different shapes and chemical structures. The role of these proteins--as simple transporters or receptor triggers--is still a matter of debate, but some recent data seem to support the latter"
Keywords:"Amino Acid Sequence Animal Communication Animals Binding Sites/genetics Insect Proteins/chemistry/genetics/physiology Insecta/chemistry/genetics/*physiology Models, Molecular Molecular Sequence Data Protein Structure, Tertiary Receptors, Odorant/*chemistr;"
Notes:"MedlineTegoni, Mariella Campanacci, Valerie Cambillau, Christian eng Review England 2004/05/08 Trends Biochem Sci. 2004 May; 29(5):257-64. doi: 10.1016/j.tibs.2004.03.003"

 
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