« Previous AbstractSamuel Thomas von Sommerring's Contributions on the Cranial Nerves and Vomeronasal Organ    Next Abstract"Predictive value of human biomonitoring in environmental medicine: experiences at the outpatient unit of environmental medicine (UEM) of the University Hospital Aachen, Germany" »

Handb Clin Neurol

Title:		"The vomeronasal organ: History, development, morphology, and functional neuroanatomy"
Author(s):		Stoyanov GS; Sapundzhiev NR; Tonchev AB;
Address:		"Department of General and Clinical Pathology, Forensic Medicine and Deontology, Faculty of Medicine, Medical University, Varna, Bulgaria. Electronic address: georgi.geesh@gmail.com. Department of Neurosurgery and ENT Diseases, Division of ENT Diseases, Faculty of Medicine, Medical University, Varna, Bulgaria. Department of Anatomy and Cell Biology, Faculty of Medicine, Medical University, Varna, Bulgaria"
Journal Title:		Handb Clin Neurol
Year:		2021
Volume:		182
Issue:
Page Number:		283 - 291
DOI:		10.1016/B978-0-12-819973-2.00020-4
ISSN/ISBN:		0072-9752 (Print) 0072-9752 (Linking)
Abstract:		"The human vomeronasal organ (VNO) is an accessory olfactory organ located on the anteroinferior part of the nasal septum, 1.5-2.5cm from the nostrils. Its main role is pheromone reception and, through its anatomical connections with the central nervous system, especially parts of the hypothalamus, modulation of both social and sexual behavior, although these relations have been established only in nonprimates and very little is yet established for the structure and function of the human VNO. Morphologically, the human VNO is a pit or duct-shaped structure, comprised of three cellular layers-basal cells, neural cells with olfactory cell morphology and immunohistochemical phenotype, and ciliated respiratory epithelium. Medially and connected to the VNO, a small nerve fiber is found that runs longitudinally to the nasal septum and is considered by some to be a distant process of the Cranial Nerve 0 or terminal nerve. In addition to pheromone reception, the human VNO has also been associated with several pathological conditions, including sinus septi nasi, posttraumatic stress disorder, and ectopic olfactory esthesioblastoma"
Keywords:		Humans Nasal Cavity Neuroanatomy Nose Smell *Vomeronasal Organ Ectopic olfactory esthesioblastoma Esthesiocytes Olfaction Pheromone reception Posttraumatic stress disorder Terminal nerve Vomeronasal organ;
Notes:		"MedlineStoyanov, George S Sapundzhiev, Nikolay R Tonchev, Anton B eng Review Netherlands 2021/07/17 Handb Clin Neurol. 2021; 182:283-291. doi: 10.1016/B978-0-12-819973-2.00020-4"