| Title: | The role of human and mosquito behaviour in the efficacy of a house-based intervention |
| Author(s): | Barreaux AMG; Oumbouke WA; Brou N; Tia IZ; Ahoua Alou LP; Doudou DT; Koffi AA; N'Guessan R; Sternberg ED; Thomas MB; |
| Address: | "Center for Infectious Disease Dynamics and Department of Entomology, Pennsylvania State University, University Park, PA 16802, USA. School of Biological Sciences, University of Bristol, Bristol BS8 1TQ, UK. Institut Pierre Richet/Institut National de Sante Publique (INSP), Bouake, Cote d'Ivoire. London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK. Centre de recherche pour le Developpement (CRD)/Laboratoire de Sante, Nutrition et Hygiene, Universite Alassane Ouattara, Bouake BP V 18 01, Cote d'Ivoire. Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK" |
| Journal Title: | Philos Trans R Soc Lond B Biol Sci |
| ISSN/ISBN: | 1471-2970 (Electronic) 0962-8436 (Print) 0962-8436 (Linking) |
| Abstract: | "Housing improvement such as blocking eaves and screening windows can help in reducing exposure to indoor biting mosquitoes. The impacts of physical barriers could potentially be boosted by the addition of a mechanism that kills mosquitoes as they attempt to enter the house. One example is to combine household screening with EaveTubes, which are insecticide-treated tubes inserted into closed eaves that attract and kill host-searching mosquitoes. The epidemiological impact of screening + EaveTubes is being evaluated in a large cluster randomized trial in Cote d'Ivoire. The study presented here is designed as a complement to this trial to help better understand the functional roles of screening and EaveTubes. We began by evaluating householder behaviour and household condition in the study villages. This work revealed that doors (and to some extent windows) were left open for large parts of the evening and morning, and that even houses modified to make them more 'mosquito proof' often had possible entry points for mosquitoes. We next built two realistic experimental houses in a village to enable us to explore how these aspects of behaviour and household quality affected the impact of screening and EaveTubes. We found that screening could have a substantial impact on indoor mosquito densities, even with realistic household condition and behaviour. By contrast, EaveTubes had no significant impact on indoor mosquito density, either as a stand-alone intervention or in combination with screening. However, there was evidence that mosquitoes recruited to the EaveTubes, and the resulting mortality could create a community benefit. These complementary modes of action of screening and EaveTubes support the rationale of combining the technologies to create a 'Lethal House Lure'. This article is part of the theme issue 'Novel control strategies for mosquito-borne diseases'" |
| Keywords: | "Animals Behavior, Animal Cote d'Ivoire *Culicidae *Housing Human Activities Humans Mosquito Control/*methods *Mosquito Vectors Randomized Controlled Trials as Topic EaveTubes housing improvement human behaviour mosquito behaviour screening vector control;" |
| Notes: | "MedlineBarreaux, Antoine M G Oumbouke, Welbeck A Brou, N'Guessan Tia, Innocent Zran Ahoua Alou, Ludovic P Doudou, Dimi Theodore Koffi, Alphonsine A N'Guessan, Raphael Sternberg, Eleanore D Thomas, Matthew B eng Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. England 2020/12/29 Philos Trans R Soc Lond B Biol Sci. 2021 Feb 15; 376(1818):20190815. doi: 10.1098/rstb.2019.0815. Epub 2020 Dec 28" |
