Title: | Modeling-based determination of physiological parameters of systemic VOCs by breath gas analysis: a pilot study |
Author(s): | Unterkofler K; King J; Mochalski P; Jandacka M; Koc H; Teschl S; Amann A; Teschl G; |
Address: | "Breath Research Institute, University of Innsbruck, Rathausplatz 4, A-6850 Dornbirn, Austria. University of Applied Sciences Vorarlberg, Hochschulstr. 1, A-6850 Dornbirn, Austria" |
DOI: | 10.1088/1752-7155/9/3/036002 |
ISSN/ISBN: | 1752-7163 (Electronic) 1752-7155 (Print) 1752-7155 (Linking) |
Abstract: | In this paper we develop a simple two compartment model which extends the Farhi equation to the case when the inhaled concentration of a volatile organic compound (VOC) is not zero. The model connects the exhaled breath concentration of systemic VOCs with physiological parameters such as endogenous production rates and metabolic rates. Its validity is tested with data obtained for isoprene and inhaled deuterated isoprene-D5 |
Keywords: | "Acetone/*chemistry Breath Tests/*instrumentation/methods Butadienes/*chemistry Exhalation/*physiology Female Hemiterpenes/*chemistry Humans Male *Models, Theoretical Pentanes/*chemistry Pilot Projects Volatile Organic Compounds/*chemistry;" |
Notes: | "MedlineUnterkofler, Karl King, Julian Mochalski, Pawel Jandacka, Martin Koc, Helin Teschl, Susanne Amann, Anton Teschl, Gerald eng P 24736/FWF_/Austrian Science Fund FWF/Austria Research Support, Non-U.S. Gov't England 2015/05/15 J Breath Res. 2015 May 14; 9(3):036002. doi: 10.1088/1752-7155/9/3/036002" |