Title: | Bespoke behavior: mechanisms that modulate pheromone-triggered behavior |
Address: | "Department of Neuroscience, Scripps Research, La Jolla, CA, USA. Department of Neuroscience, Scripps Research, La Jolla, CA, USA. Electronic address: stowers@scripps.edu" |
DOI: | 10.1016/j.conb.2020.05.003 |
ISSN/ISBN: | 1873-6882 (Electronic) 0959-4388 (Print) 0959-4388 (Linking) |
Abstract: | "What is good for others, may not be in my best interest. Individuals should not, and do not, respond identically in the same environment. Personalized social behavior is particularly important to ultimately ensure reproductive fitness. How and where neural activity is modulated to customize behavior has remained largely unknown. The robust response to pheromones provides a platform to identify the logic of how the brain initiates social behavior. Mouse pheromones engage innate motor actions that underlie social behavior yet are plastic to suit individual needs. Recent study of mouse pheromone behavior, neurocircuit activity, and functional manipulations is beginning to paint a complex, dynamic, and diverse picture of the mechanisms that enable flexible modulation of social behavior" |
Keywords: | "Animals Behavior, Animal Brain Mice *Pheromones *Social Behavior;" |
Notes: | "MedlineTan, Shawn Stowers, Lisa eng R01 DC015253/DC/NIDCD NIH HHS/ R01 NS108439/NS/NINDS NIH HHS/ Research Support, N.I.H., Extramural Review England 2020/07/19 Curr Opin Neurobiol. 2020 Oct; 64:143-150. doi: 10.1016/j.conb.2020.05.003. Epub 2020 Jul 15" |