| Title: | Chemo-Diversity and Antiradical Potential of Twelve Matricaria chamomilla L. Populations from Iran: Proof of Ecological Effects |
| Author(s): | Piri E; Mahmoodi Sourestani M; Khaleghi E; Mottaghipisheh J; Zomborszki ZP; Hohmann J; Csupor D; |
| Address: | "Department of Horticultural Science, Faculty of Agriculture, Shahid Chamran University of Ahvaz, Ahvaz 61357-43311, Iran. elahe.73.piri@gmail.com. Department of Horticultural Science, Faculty of Agriculture, Shahid Chamran University of Ahvaz, Ahvaz 61357-43311, Iran. mohammad.mahmoodi1360@gmail.com. Department of Horticultural Science, Faculty of Agriculture, Shahid Chamran University of Ahvaz, Ahvaz 61357-43311, Iran. khaleghi2184@gmail.com. Department of Pharmacognosy, University of Szeged, Eotvos u. 6, H-6720 Szeged, Hungary. Imanmottaghipisheh@pharmacognosy.hu. Department of Pharmacognosy, University of Szeged, Eotvos u. 6, H-6720 Szeged, Hungary. zombozope@pharmacognosy.hu. Department of Pharmacognosy, University of Szeged, Eotvos u. 6, H-6720 Szeged, Hungary. hohmann@pharm.u-szeged.hu. Department of Pharmacognosy, University of Szeged, Eotvos u. 6, H-6720 Szeged, Hungary. csupor.dezso@pharmacognosy.hu" |
| DOI: | 10.3390/molecules24071315 |
| ISSN/ISBN: | 1420-3049 (Electronic) 1420-3049 (Linking) |
| Abstract: | "Matricaria chamomilla L. is a popular medicinal herb that is used for healing various diseases and is widely distributed worldwide in temperate climate zones, and even in the subtropical climate of Southern and Western Iran. This study was aimed at comparing the volatile oil constituents, along with antiradical potential and HPLC analysis of methanolic extracts from twelve plant samples growing in Iran. The present research was carried out for the first time on these populations. Among seventeen identified volatile chemicals evaluated by GC/MS and GC/FID, representing 92.73-97.71% of the total oils, alpha-bisabolone oxide A (45.64-65.41%) was the major constituent, except in case of 'Sarableh' as a new chemotype, where (E)- and (Z)-gamma-bisabolene (42.76 and 40.08%, respectively) were the predominant components. Oxygenated sesquiterpenes (53.31-74.52%) were the most abundant compounds in the samples excluding 'Sarableh' with 91.3% sesquiterpene hydrocarbons. 'Sarableh' also exerted the most potent antioxidant capacity with EC(50) = 7.76 +/- 0.3 microg/mL and 6.51 +/- 0.63 mmol TE (Trolox((R)) equivalents)/g. In addition, populations 'Lali' and 'Bagh Malek' contained the highest amounts of apigenin and luteolin with 1.19 +/- 0.01 mg/g and 2.20 +/- 0.0 mg/g of plant material, respectively. Our findings depict a clear correlation between phytochemical profiles and antiradical potential of M. chamomilla and geographical factors" |
| Keywords: | "Antioxidants/*chemistry/pharmacology Apigenin/chemistry Environment Iran Luteolin/chemistry Matricaria/*chemistry Oils, Volatile/analysis/chemistry/pharmacology Phytochemicals/analysis/*chemistry Plant Extracts/*chemistry/pharmacology Volatile Organic Com;" |
| Notes: | "MedlinePiri, Elahe Mahmoodi Sourestani, Mohammad Khaleghi, Esmaeil Mottaghipisheh, Javad Zomborszki, Zoltan Peter Hohmann, Judit Csupor, Dezso eng none/Shahid Chamran University of Ahvaz/ OTKA K115796/National Research, Development and Innovation Office/ GINOP-2.3.2-15-2016-00012/Economic Development and Innovation Operative Programme/ Janos Bolyai Research Scholarship/Hungarian Academy of Sciences/ Switzerland 2019/04/17 Molecules. 2019 Apr 3; 24(7):1315. doi: 10.3390/molecules24071315" |
