| Title: | Courtship vocalizations: A potential biomarker of adult exposure to endocrine disrupting compounds? |
| Address: | "Sorbonne Universite, CNRS UMR 8246, INSERM U1130, Neuroscience Paris Seine - Institut de Biologie Paris-Seine, 7 quai St Bernard, Bat A 3eme etage, 75005, Paris, France. Electronic address: sakina.mhaouty-kodja@upmc.fr" |
| DOI: | 10.1016/j.mce.2019.110664 |
| ISSN/ISBN: | 1872-8057 (Electronic) 0303-7207 (Linking) |
| Abstract: | "In rodents, male courtship is stimulated by pheromones emitted by the sexually receptive female. In response, the male produces ultrasonic vocalizations, which appear to play a role in female attraction and facilitate copulation. The present review summarizes the main findings on courtship vocalizations and their tight regulation by sex steroid hormones. It describes studies that address the effects of exposure to endocrine disrupting compounds (EDC) on ultrasound production, as changes in hormone levels or their signaling pathways may interfere with the emission of ultrasonic vocalizations. It also discusses the potential use of this behavior as a noninvasive biomarker of adult exposure to EDC" |
| Keywords: | "Animals Biomarkers/*metabolism *Courtship Endocrine Disruptors/*adverse effects Gonadal Steroid Hormones/*metabolism Humans Signal Transduction/physiology Ultrasonics/methods Vocalization, Animal/*physiology Behavior Courtship Endocrine disruption Rodents;neuroscience;" |
| Notes: | "MedlineMhaouty-Kodja, Sakina eng Research Support, Non-U.S. Gov't Review Ireland 2019/11/26 Mol Cell Endocrinol. 2020 Feb 5; 501:110664. doi: 10.1016/j.mce.2019.110664. Epub 2019 Nov 22" |
