| Title: | Blood concentrations of volatile organic compounds in a nonoccupationally exposed US population and in groups with suspected exposure |
| Author(s): | Ashley DL; Bonin MA; Cardinali FL; McCraw JM; Wooten JV; |
| Address: | "Division of Environmental Health Laboratory Sciences, Centers for Disease Control and Prevention, Atlanta, GA 30341-3724" |
| ISSN/ISBN: | 0009-9147 (Print) 0009-9147 (Linking) |
| Abstract: | "Exposure to certain volatile organic compounds (VOCs) commonly occurs in industrialized countries. We developed a method for measuring 32 VOCs in 10 mL of whole blood at low concentration. We used this method to determine the internal dose of these compounds in 600 or more people in the US who participated in the Third National Health and Nutrition Examination Survey. From our study results, we established a reference range for these VOCs in the general population of the US. We found detectable concentrations of 1,1,1-trichloroethane, 1,4-dichlorobenzene, 2-butanone, acetone, benzene, chloroform, ethylbenzene, m,p-xylene, styrene, tetrachloroethane, and toluene in most of the blood samples of nonoccupationally exposed persons. The accuracy of VOC evaluations depends on the ability of investigators to make sensitive and reproducible measurements of low concentrations of VOCs and to eliminate all sources of interference and contamination" |
| Keywords: | *Environmental Exposure Environmental Pollutants/*blood/pharmacokinetics Humans Hydrocarbons/*blood/pharmacokinetics Reference Values United States Volatilization; |
| Notes: | "MedlineAshley, D L Bonin, M A Cardinali, F L McCraw, J M Wooten, J V eng Research Support, U.S. Gov't, P.H.S. England 1994/07/01 Clin Chem. 1994 Jul; 40(7 Pt 2):1401-4" |
