« Previous AbstractElectrophysiological and behavioral responses of Thanatophilus sinuatus Fabricius (Coleoptera: Silphidae) to selected cadaveric volatile organic compounds    Next AbstractMoment-to-moment flight manoeuvres of the female yellow fever mosquito (Aedes aegypti L.) in response to plumes of carbon dioxide and human skin odour »

Parasit Vectors

Title:		Identification of mosquito repellent odours from Ocimum forskolei
Author(s):		Dekker T; Ignell R; Ghebru M; Glinwood R; Hopkins R;
Address:		"Division of Chemical Ecology, Department of Crop Science, Swedish University of Agricultural Sciences PO 44, Alnarp, SE-23053, Sweden. teun.dekker@slu.se"
Journal Title:		Parasit Vectors
Year:		2011
Volume:		20110922
Issue:
Page Number:		183 -
DOI:		10.1186/1756-3305-4-183
ISSN/ISBN:		1756-3305 (Electronic) 1756-3305 (Linking)
Abstract:		"BACKGROUND: Native mosquito repellent plants have a good potential for integrated mosquito control in local settings. Ocimum forskolei, Lamiaceae, is used in Eritrea as a spatial mosquito repellent inside houses, either through crushing fresh plants or burning dry plants. We verified whether active repellent compounds could be identified using gas-chromatography coupled electroantennogram recordings (GC-EAD) with headspace extracts of crushed plants. RESULTS: EAD active compounds included (R)-(-)-linalool, (S)-(+)-1-octen-3-ol, trans-caryophyllene, naphthalene, methyl salicylate, (R)-(-)-alpha-copaene, methyl cinnamate and (E)-ocimene. Of these compounds (R)-(-)-linalool, methyl cinnamate and methyl salicylate reduced landing of female Aedes aegypti on human skin-odor baited tubes. The latter two are novel mosquito repellent compounds. CONCLUSIONS: The identification of mosquito repellent compounds contributes to deciphering the mechanisms underlying repulsion, supporting the rational design of novel repellents. The three mosquito repellent compounds identified in this study are structurally dissimilar, which may indicate involvement of different sensory neurons in repulsion. Repulsion may well be enhanced through combining different repellent plants (or their synthetic mimics), and can be a locally sustainable part in mosquito control efforts"
Keywords:		Aedes/*drug effects/physiology Animals Female Gas Chromatography-Mass Spectrometry Insect Repellents/*chemistry/pharmacology Male Mosquito Control Ocimum/*chemistry Odorants/*analysis Plant Extracts/*chemistry/pharmacology Volatile Organic Compounds/*chem;
Notes:		"MedlineDekker, Teun Ignell, Rickard Ghebru, Maedot Glinwood, Robert Hopkins, Richard eng Research Support, Non-U.S. Gov't England 2011/09/23 Parasit Vectors. 2011 Sep 22; 4:183. doi: 10.1186/1756-3305-4-183"