« Previous Abstract"[The female pheromone 2,5-dimethylpyrazine induces sperm head abnormalities in male CBA mice]"    Next Abstract"[Immunological, cytogenetic and behavior changes in male mice CBA and C57BL/6 exposed to pheromone]" »

Genetika

Title:		[Induction of dominant lethals in progeny of male CBA mice after pheromonal action]
Author(s):		Daev EV;
Address:		"Department of Genetics and Breeding, St. Petersburg State University, St. Petersburg, 199034 Russia. edaev@motmail.com"
Journal Title:		Genetika
Year:		2003
Volume:		39
Issue:		10
Page Number:		1347 - 1352
DOI:
ISSN/ISBN:		0016-6758 (Print) 0016-6758 (Linking)
Abstract:		"The inhibiting effect of pheromone 2,5-dimethylpyrazine of house mouse females on the reproductive function of the CBA male mice was studied. The mutagenic effect of six-day pheromonal effect was assessed by dominant lethal test. Analysis for the frequency of dominant lethals showed that the pheromonal effect results in an increased death rate of the progeny of the treated males. This is probably explained by implantation failure and is expressed in a reduced average number of the implantation sites and low live embryos per female. The proportion of females with live embryos decreased significantly. The implication of the effect of female mouse pheromone 2,5-dimethylpyrazine on the genetic processes in germ cells of male mice is discussed"
Keywords:		"Animals *Genes, Dominant Male Mice Mice, Inbred CBA Pheromones/*physiology;"
Notes:		"MedlineDaev, E V rus English Abstract Russia (Federation) 2003/12/09 Genetika. 2003 Oct; 39(10):1347-52"