| Title: | Rapid and accurate determination of trace volatile sulfur compounds in human halitosis by an adaptable active sampling system coupling with gas chromatography |
| Author(s): | Xu Y; Yu Z; Chen X; Zhou Y; Zhou K; Zhang Z; Li G; |
| Address: | "School of Chemistry, Sun Yat-sen University, Guangzhou, China. Research & Development department, Hawley & Hazel Chemical Co. (Zhongshan) Ltd., Zhongshan, P.R. China" |
| ISSN/ISBN: | 1615-9314 (Electronic) 1615-9306 (Linking) |
| Abstract: | "Halitosis with the main components of trace volatile sulfur compounds widely affects the quality of life. In this study, an adaptable active sampling system with two sample-collection modes of direct injection and solid-phase microextraction was developed for the rapid and precise determination of trace volatile sulfur compounds in human halitosis coupled with gas chromatography-flame photometric detection. The active sampling system was well designed and produced for efficiently sampling and precisely determining trace volatile targets in halitosis under the optimized sampling and detection conditions. The analytical method established was successfully applied for the determination of trace targets in halitosis. The limits of detection of H(2) S, CH(3) SH, and CH(3) SCH(3) by direct injection were 0.0140-23.0 mug/L with good recoveries ranging from 82.2 to 118% and satisfactory relative standard deviations of 0.4-9.5% (n = 3), respectively. The limit of detections of CH(3) SH and CH(3) SCH(3) by solid-phase microextraction were 2.03 and 0.186 x 10(-3) mug/L with good recoveries ranging from 98.3 to 108% and relative standard deviations of 5.9-9.0% (n = 3). Trace volatile targets in positive real samples could be actually found and quantified by combination of direct injection and solid-phase microextraction. This method was reliable and efficient for the determination of trace volatile sulfur compounds in halitosis" |
| Keywords: | "Chromatography, Gas Halitosis/*diagnosis Humans Solid Phase Microextraction Sulfur Compounds/*analysis Volatile Organic Compounds/*analysis active sampling system gas chromatography halitosis solid-phase microextraction volatile sulfur compounds;" |
| Notes: | "MedlineXu, Yu Yu, Zhongning Chen, Xiaobin Zhou, Yi Zhou, Kang Zhang, Zhuomin Li, Gongke eng 21475154, 21675178, and 21976213/National Natural Science Foundation of China/ 2019A1515010107/Guangdong Basic and Applied Basic Research Foundation/ 2019B020211001/Research and Development Plan for Key Areas of Food Safety in Guangdong Province of China/ 14324100-201712-9816/Research Funding from Hawley & Hazel Chemical Co. (Zhongshan) Ltd./ 21475154/National Natural Science Foundation of China/ 21675178/National Natural Science Foundation of China/ 21976213/National Natural Science Foundation of China/ Germany 2020/01/21 J Sep Sci. 2020 May; 43(9-10):1830-1837. doi: 10.1002/jssc.201901191. Epub 2020 Feb 4" |
