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Georgian Med News


Title:[Role of Fecal Volatile Organic Compounds in the Diagnosis of Bronchopulmonary Dysplasia]
Author(s):Syzdykova M; Morenko M; Gatauova M; Temirkhnova R; Shnaider K;
Address:"NAO 'Medical University Astana', Nur-Sultan, Kazakhstan"
Journal Title:Georgian Med News
Year:2020
Volume:
Issue:308
Page Number:80 - 84
DOI:
ISSN/ISBN:1512-0112 (Print) 1512-0112 (Linking)
Abstract:"The aim of the study was to analyze fecal volatile organic compounds in premature babies born with a weight of less than 1,500 grams in order to identify predictors of BPD. The study presents the results of the study in parallel groups, which are represented by premature babies born with a weight of less than 1500 grams. In the course of scientific work, 137 children were examined, from which stool samples were taken on the 14th and 28th days of life to detect VOCs using gas chromatography with mass spectrometry (GC/MS). The Torion T-9 GC / MS was used to separate and identify the VOCs present in the feces of the subjects. After sampling, these children were further divided into two groups: group I (main) - children who realized BPD (n=89) and group II (control) - children who did not realize BPD (n=48). During the study, 28 VOCs were found in the feces of the subjects on the 14th and 28th days of life, among which the three most significant were identified, among them tetradecane, N-nitrosopyrrolidine, and trichloretene"
Keywords:"*Bronchopulmonary Dysplasia Child Feces Gas Chromatography-Mass Spectrometry Humans Infant, Newborn Infant, Premature *Volatile Organic Compounds/analysis;"
Notes:"MedlineSyzdykova, M Morenko, M Gatauova, M Temirkhnova, R Shnaider, K rus Georgia (Republic) 2021/01/05 Georgian Med News. 2020 Nov; (308):80-84"

 
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