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Curr Genet

Title:		Strains isogenic to S288C used in the yeast genome sequencing programme carry a functional KSS1 gene
Author(s):		Morillon A; Springer M; Lesage P;
Address:		"UPR 9073 du CNRS, Institut de Biologie Physico-Chimique, Paris, France"
Journal Title:		Curr Genet
Year:		2001
Volume:		39
Issue:		5-Jun
Page Number:		291 - 296
DOI:		10.1007/s002940100222
ISSN/ISBN:		0172-8083 (Print) 0172-8083 (Linking)
Abstract:		"In Saccharomyces cerevisiae, the KSS1 gene encodes the MAP kinase of the invasive/filamentous growth pathway. In addition to its role in this signal transduction pathway, Kssl can replace the Fus3 MAP kinase in the pheromone-response pathway, in the absence of FUS3. Previous work indicated that derivatives of the S288C strain carry a mutant kss1 allele. Here, we report evidence that S288C derivatives used in the Yeast Genome Sequencing Programme carry a functional KSS1 gene and can thus be used to study the regulation of gene expression by KSS1"
Keywords:		"Amino Acid Sequence Amino Acid Substitution Fungal Proteins/chemistry/*genetics/metabolism *Genome, Fungal Genotype Mitogen-Activated Protein Kinases/chemistry/*genetics/metabolism Molecular Sequence Data Mutagenesis, Site-Directed Pheromones/physiology R;"
Notes:		"MedlineMorillon, A Springer, M Lesage, P eng Research Support, Non-U.S. Gov't 2001/08/30 Curr Genet. 2001 Jul; 39(5-6):291-6. doi: 10.1007/s002940100222"