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Clin Chem


Title:Volatile organic compounds in exhaled air from patients with lung cancer
Author(s):Gordon SM; Szidon JP; Krotoszynski BK; Gibbons RD; O'Neill HJ;
Address:
Journal Title:Clin Chem
Year:1985
Volume:31
Issue:8
Page Number:1278 - 1282
DOI:
ISSN/ISBN:0009-9147 (Print) 0009-9147 (Linking)
Abstract:"Using a specially developed breath collection technique and computer-assisted gas chromatography/mass spectrometry (GC/MS), we have identified in the exhaled air of lung cancer patients several volatile organic compounds that appear to be associated with the disease. The GC/MS profiles of 12 samples from lung cancer patients and 17 control samples were analyzed by using general computerized statistical procedures to distinguish lung cancer patients from controls. The selected volatile compounds had sufficient diagnostic power in the GC/MS profiles to allow almost complete differentiation between the two groups in a limited patient population"
Keywords:"Adenocarcinoma/physiopathology Aged *Breath Tests Carcinoma, Squamous Cell/physiopathology Computers Female Gas Chromatography-Mass Spectrometry Humans Lung Neoplasms/*physiopathology Male Middle Aged;"
Notes:"MedlineGordon, S M Szidon, J P Krotoszynski, B K Gibbons, R D O'Neill, H J eng England 1985/08/01 Clin Chem. 1985 Aug; 31(8):1278-82"

 
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