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J Hazard Mater

Title:		Effect of ionic liquid on the toxicity of pesticide to Vibrio-qinghaiensis sp.-Q67
Author(s):		Zhang J; Liu SS; Liu HL;
Address:		"Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, PR China"
Journal Title:		J Hazard Mater
Year:		2009
Volume:		20090521
Issue:		2-Mar
Page Number:		920 - 927
DOI:		10.1016/j.jhazmat.2009.05.056
ISSN/ISBN:		1873-3336 (Electronic) 0304-3894 (Linking)
Abstract:		"Ionic liquids (ILs) are novel green chemicals and used to replace traditional volatile organic solvents in industrial processes. Yet the potential effects of ILs on the toxicities of chemicals such as pesticides had been poorly studied. The aim of this paper is to determine the joint toxicity between IL and pesticide. Desmetryn (DES) and dichlorvos (DIC) were chosen as representatives of pesticides and 1-butyl-2,3-dimethylimidazolium chloride (IL1) and 1-butyl-pyridinium bromide (IL2) as those of ILs. The toxicities of the pesticides and ILs as well as their binary mixtures on Vibrio-qinghaiensis sp.-Q67 were determined using the microplate toxicity analysis. A simplified central composite design (SCCD) was employed to design the concentration distribution of components in binary mixtures to effectively detect the possible toxic interactions between pesticide and IL over the whole concentration range. Results showed that all the binary mixtures between pesticide and IL exhibited a similar toxicity action rule, i.e., displayed a synergistic interaction in a high concentration region, an additive action in a medium concentration region, and an antagonistic interaction in a low concentration region. The reason how to produce the toxic interaction is still under study"
Keywords:		"Algorithms Dichlorvos/toxicity Dose-Response Relationship, Drug Drug Synergism Imidazoles/toxicity Insecticides/toxicity Ions Microbial Sensitivity Tests Pesticides/*toxicity Pyridinium Compounds/toxicity Solutions Triazines/toxicity Vibrio/*drug effects;"
Notes:		"MedlineZhang, Jing Liu, Shu-Shen Liu, Hai-Ling eng Research Support, Non-U.S. Gov't Netherlands 2009/06/13 J Hazard Mater. 2009 Oct 30; 170(2-3):920-7. doi: 10.1016/j.jhazmat.2009.05.056. Epub 2009 May 21"