| Title: | Liquid chromatography-flame ionisation detection using a nebuliser/spray chamber interface. Part 1. Design and testing |
| Author(s): | Young E; Smith RM; Sharp BL; Bone JR; |
| Address: | "Department of Chemistry, Loughborough University, Loughborough, Leicestershire, LE11 3TU, UK" |
| DOI: | 10.1016/j.chroma.2012.02.033 |
| ISSN/ISBN: | 1873-3778 (Electronic) 0021-9673 (Linking) |
| Abstract: | "A nebuliser and spray chamber have been used to link a flow injection analyser to a flame ionisation detector, with the potential for the combination to be used as a universal detector for liquid chromatography. The hydrogen and air flows were adjusted to achieve a stable system. The detector responded to both volatile and involatile analytes and to compounds with and without chromophores, including alkanes, alkanols, aromatic amides and acids, phenols, amino-acids and carbohydrates and gave a linear response for many analytes. However, for involatile polar analytes it was necessary to add traces of acid or salt to the carrier stream to obtain a linear response" |
| Keywords: | "Chromatography, Liquid/*instrumentation/*methods Equipment Design Flame Ionization/*instrumentation Flow Injection Analysis/*instrumentation Hydrogen/chemistry Hydrogen-Ion Concentration Linear Models *Nebulizers and Vaporizers Organic Chemicals/analysis/;" |
| Notes: | "MedlineYoung, Erepamowei Smith, Roger M Sharp, Barry L Bone, Joanne R eng Research Support, Non-U.S. Gov't Netherlands 2012/03/14 J Chromatogr A. 2012 May 4; 1236:16-20. doi: 10.1016/j.chroma.2012.02.033. Epub 2012 Feb 19" |
