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Int J Food Microbiol

Title:		Antimycotoxigenic characteristics of Rosmarinus officinalis and Trachyspermum copticum L. essential oils
Author(s):		Rasooli I; Fakoor MH; Yadegarinia D; Gachkar L; Allameh A; Rezaei MB;
Address:		"Department of Biology, Shahed University, Tehran-Qom Express Way, Opposite Imam Khomeini's shrine, Tehran-3319118651, Iran. rasooli@shahed.ac.ir"
Journal Title:		Int J Food Microbiol
Year:		2008
Volume:		20071129
Issue:		1-Feb
Page Number:		135 - 139
DOI:		10.1016/j.ijfoodmicro.2007.11.048
ISSN/ISBN:		0168-1605 (Print) 0168-1605 (Linking)
Abstract:		"Aflatoxin B1 (AFB1) is a highly toxic and carcinogenic metabolite produced by Aspergillus species on food and agricultural commodities. Natural products may regulate the cellular effects of aflatoxins and evidence suggests that aromatic organic compounds of spices can control the production of aflatoxins. With a view to controlling aflatoxin production, the essential oils from Rosmarinus officinalis and Trachyspermum copticum L. were obtained by hydrodistillation. Antifungal activities of the oils were studied with special reference to the inhibition of Aspergillus parasiticus growth and aflatoxin production. Minimal inhibitory (MIC) and minimal fungicidal (MFC) concentrations of the oils were determined. T. copticum L. oil showed a stronger inhibitory effect than R. officinalis on the growth of A. parasiticus. Aflatoxin production was inhibited at 450 ppm of both oils with that of R. officinalis being stronger inhibitor. The oils were analyzed by GC and GC/MS. The major components of R. officinalis and T. copticum L. oils were Piperitone (23.65%), alpha-pinene (14.94%), Limonene (14.89%), 1,8-Cineole (7.43%) and Thymol (37.2%), P-Cymene (32.3%), gamma-Terpinene (27.3%) respectively. It is concluded that the essential oils could be safely used as preservative materials on some kinds of foods to protect them from toxigenic fungal infections"
Keywords:		"Aflatoxin B1/biosynthesis Antifungal Agents/*pharmacology Apiaceae/*chemistry Aspergillus/*drug effects/growth & development/metabolism Colony Count, Microbial Dose-Response Relationship, Drug Food Preservation/methods Food Preservatives/pharmacology Micr;"
Notes:		"MedlineRasooli, Iraj Fakoor, Mohammad Hadi Yadegarinia, Davod Gachkar, Latif Allameh, Abdolamir Rezaei, Mohammad Bagher eng Research Support, Non-U.S. Gov't Netherlands 2008/01/15 Int J Food Microbiol. 2008 Feb 29; 122(1-2):135-9. doi: 10.1016/j.ijfoodmicro.2007.11.048. Epub 2007 Nov 29"