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J Chem Ecol

Title:		Adaptation to nicotine feeding in Myzus persicae
Author(s):		Ramsey JS; Elzinga DA; Sarkar P; Xin YR; Ghanim M; Jander G;
Address:		"Boyce Thompson Institute, Ithaca, NY, 14853, USA"
Journal Title:		J Chem Ecol
Year:		2014
Volume:		20140801
Issue:		8
Page Number:		869 - 877
DOI:		10.1007/s10886-014-0482-5
ISSN/ISBN:		1573-1561 (Electronic) 0098-0331 (Print) 0098-0331 (Linking)
Abstract:		"Lineages of the generalist hemipteran herbivore Myzus persicae (green peach aphid) that have expanded their host range to include tobacco often have elevated nicotine tolerance. The tobacco-adapted M. persicae lineage used in this study was able to reproduce on nicotine-containing artificial diets at concentrations that were 15-fold higher than those that were lethal to a non-adapted M. persicae lineage. Fecundity of the nicotine-tolerant M. persicae lineage was increased by 100 muM nicotine in artificial diet, suggesting that this otherwise toxic alkaloid can serve as a feeding stimulant at low concentrations. This lineage also was pre-adapted to growth on tobacco, exhibiting no drop in fecundity when it was moved onto tobacco from a different host plant. Although growth of the non-tobacco-adapted M. persicae lineage improved after three generations on tobacco, this higher reproductive rate was not associated with increased nicotine tolerance. Myzus persicae gene expression microarrays were used to identify transcripts that are up-regulated in response to nicotine in the tobacco-adapted lineage. Induced expression was found for CYP6CY3, which detoxifies nicotine in M. persicae, other genes encoding known classes of detoxifying enzymes, and genes encoding secreted M. persicae salivary proteins"
Keywords:		"*Adaptation, Physiological Animals Aphids/genetics/growth & development/*physiology Diet *Feeding Behavior *Food Chain Nicotine/*metabolism Tobacco/chemistry;"
Notes:		"MedlineRamsey, John S Elzinga, Dezi A Sarkar, Pooja Xin, Yi-Ran Ghanim, Murad Jander, Georg eng T32 GM008500/GM/NIGMS NIH HHS/ 5T32GM008500/GM/NIGMS NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. 2014/08/02 J Chem Ecol. 2014 Aug; 40(8):869-77. doi: 10.1007/s10886-014-0482-5. Epub 2014 Aug 1"