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Gerontology

Title:		Difference in the responsiveness of old female rats to estrogen to secrete sex attractants as a function of different reproductive states
Author(s):		Peng MT; Mu SC;
Address:		"Department of Physiology, College of Medicine, National Taiwan University, Taipei, Republic of China"
Journal Title:		Gerontology
Year:		1988
Volume:		34
Issue:		3
Page Number:		110 - 114
DOI:		10.1159/000212938
ISSN/ISBN:		0304-324X (Print) 0304-324X (Linking)
Abstract:		Two age groups of Long-Evans rats (young: 3.5-7 months of age and old: over 23 months of age) were ovariectomized and implanted subcutaneously with a 1:2 estradiol benzoate (E2)-cholestrol mixture-filled Silastic capsule. Olfactory preference of male partners to these female rats over ovariectomized young rats without E2 replacement was examined. Olfactory preference of adult male rats as indicated by investigation frequency and investigation time for old pseudopregnancy (PSP) rats and long-term ovariectomized rats was decreased but not that of prolonged-vaginal-cornification (PVC) rats when compared with young female rats. These results indicate that the responsiveness of old PVC rats to estrogen to secrete sex attractants is not decreased but that of PSP rats and long-term ovariectomized rats is decreased when compared with young female rats
Keywords:		*Aging Animals Estradiol/*physiology Female Male *Ovariectomy Pheromones/*metabolism Rats Sex Attractants/*metabolism *Smell;
Notes:		"MedlinePeng, M T Mu, S C eng Research Support, Non-U.S. Gov't Switzerland 1988/01/01 Gerontology. 1988; 34(3):110-4. doi: 10.1159/000212938"