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J Agric Food Chem

Title:		"Hippophae rhamnoides L.: A Comprehensive Review on the Botany, Traditional Uses, Phytonutrients, Health Benefits, Quality Markers, and Applications"
Author(s):		Ma QG; He NX; Huang HL; Fu XM; Zhang ZL; Shu JC; Wang QY; Chen J; Wu G; Zhu MN; Sang ZP; Cao L; Wei RR;
Address:		"Key Laboratory of Modern Preparation of Traditional Chinese Medicine of Ministry of Education, Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic Medicine, College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China. School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China"
Journal Title:		J Agric Food Chem
Year:		2023
Volume:		20230317
Issue:		12
Page Number:		4769 - 4788
DOI:		10.1021/acs.jafc.2c06916
ISSN/ISBN:		1520-5118 (Electronic) 0021-8561 (Linking)
Abstract:		"Hippophae rhamnoides L. (sea buckthorn), consumed as a food and health supplement worldwide, has rich nutritional and medicinal properties. Different parts of H. rhamnoides L. were used in traditional Chinese medicines for relieving cough, aiding digestion, invigorating blood circulation, and alleviating pain since ancient times. Phytochemical studies revealed a wide variety of phytonutrients, including nutritional components (proteins, minerals, vitamins, etc.) and functional components like flavonoids (1-99), lignans (100-143), volatile oils (144-207), tannins (208-230), terpenoids (231-260), steroids (261-270), organic acids (271-297), and alkaloids (298-305). The pharmacological studies revealed that some crude extracts or compounds of H. rhamnoides L. demonstrated various health benefits, such as anti-inflammatory, antioxidant, hepatoprotective, anticardiovascular disease, anticancer, hypoglycemic, hypolipidemic, neuroprotective, antibacterial activities, and their effective doses and experimental models were summarized and analyzed in this paper. The quality markers (Q-markers) of H. rhamnoides L. were predicted and analyzed based on protobotanical phylogeny, traditional medicinal properties, expanded efficacy, pharmacokinetics and metabolism, and component testability. The applications of H. rhamnoides L. in juice, wine, oil, ferment, and yogurt were also summarized and future prospects were examined in this review. However, the mechanism and structure-activity relationship of some active compounds are not clear, and quality control and potential toxicity are worth further study in the future"
Keywords:		"*Hippophae/chemistry Phytochemicals/pharmacology Antioxidants *Oils, Volatile *Botany Hippophae rhamnoides L.applications botany, traditional uses health benefits phytonutrients quality markers;"
Notes:		"MedlineMa, Qin-Ge He, Neng-Xin Huang, Hui-Lian Fu, Xiao-Mei Zhang, Zhong-Li Shu, Ji-Cheng Wang, Qin-Yuan Chen, Jie Wu, Guang Zhu, Mei-Ning Sang, Zhi-Pei Cao, Lan Wei, Rong-Rui eng Review 2023/03/18 J Agric Food Chem. 2023 Mar 29; 71(12):4769-4788. doi: 10.1021/acs.jafc.2c06916. Epub 2023 Mar 17"