| Title: | Clinical studies of detecting COVID-19 from exhaled breath with electronic nose |
| Author(s): | Kwiatkowski A; Borys S; Sikorska K; Drozdowska K; Smulko JM; |
| Address: | "Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, Narutowicza 11/12, 80-233, Gdansk, Poland. University Center of Maritime and Tropical Medicine, Powstania Styczniowego 9B, 81-519, Gdynia, Poland. Division of Tropical and Parasitic Diseases, Faculty of Health Sciences, Medical University of Gdansk, Powstania Styczniowego 9B, 81-519, Gdynia, Poland. Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, Narutowicza 11/12, 80-233, Gdansk, Poland. janusz.smulko@pg.edu.pl" |
| DOI: | 10.1038/s41598-022-20534-8 |
| ISSN/ISBN: | 2045-2322 (Electronic) 2045-2322 (Linking) |
| Abstract: | "The COVID-19 pandemic has attracted numerous research studies because of its impact on society and the economy. The pandemic has led to progress in the development of diagnostic methods, utilizing the polymerase chain reaction (PCR) as the gold standard for coronavirus SARS-CoV-2 detection. Numerous tests can be used at home within 15 min or so but of with lower accuracy than PCR. There is still a need for point-of-care tests available for mass daily screening of large crowds in airports, schools, and stadiums. The same problem exists with fast and continuous monitoring of patients during their medical treatment. The rapid methods can use exhaled breath analysis which is non-invasive and delivers the result quite fast. Electronic nose can detect a cocktail of volatile organic com-pounds (VOCs) induced by virus infection and disturbed metabolism in the human body. In our exploratory studies, we present the results of COVID-19 detection in a local hospital by applying the developed electronic setup utilising commercial VOC gas sensors. We consider the technical problems noticed during the reported studies and affecting the detection results. We believe that our studies help to advance the proposed technique to limit the spread of COVID-19 and similar viral infections" |
| Keywords: | Breath Tests/methods *COVID-19/diagnosis Electronic Nose Exhalation Humans Pandemics SARS-CoV-2 *Volatile Organic Compounds/analysis; |
| Notes: | "MedlineKwiatkowski, Andrzej Borys, Sebastian Sikorska, Katarzyna Drozdowska, Katarzyna Smulko, Janusz M eng Research Support, Non-U.S. Gov't England 2022/09/28 Sci Rep. 2022 Sep 26; 12(1):15990. doi: 10.1038/s41598-022-20534-8" |
