« Previous AbstractCharacterization of the Extracellular Volatile Metabolome of Pseudomonas Aeruginosa Applying an in vitro Biofilm Model under Cystic Fibrosis-Like Conditions    Next Abstract"Head, Shoulders, Knees, and Toes: Placement of Wearable Passive Samplers Alters Exposure Profiles Observed" »

Cell

Title:		Heterotrimeric G protein signaling: Getting inside the cell
Author(s):		Koelle MR;
Address:		"Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06520, USA. michael.koelle@yale.edu"
Journal Title:		Cell
Year:		2006
Volume:		126
Issue:		1
Page Number:		25 - 27
DOI:		10.1016/j.cell.2006.06.026
ISSN/ISBN:		0092-8674 (Print) 0092-8674 (Linking)
Abstract:		"Heterotrimeric G proteins have traditionally been thought to transduce signals at the plasma membrane. In this issue, Slessareva et al. (2006) now show that a G protein alpha subunit acts at the endosome to stimulate a phosphatidylinositol 3-kinase to help yeast respond to mating pheromones"
Keywords:		"Cell Membrane/genetics/metabolism Endosomes/genetics/*metabolism Heterotrimeric GTP-Binding Proteins/genetics/*metabolism Models, Biological Phosphatidylinositol 3-Kinases/*metabolism Protein Binding/physiology Reproduction, Asexual/physiology Saccharomyc;"
Notes:		"MedlineKoelle, Michael R eng Comment Review 2006/07/15 Cell. 2006 Jul 14; 126(1):25-7. doi: 10.1016/j.cell.2006.06.026"