| Title: | "First characterization of Pompia intrea candied fruit: The headspace chemical profile, polar extract composition and its biological activities" |
| Author(s): | Deiana M; Montoro P; Jerkovic I; Atzeri A; Marijanovic Z; Serreli G; Piacente S; Tuberoso CIG; |
| Address: | "Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, 554, km 4.5, Monserrato, 09042, Italy. Department of Pharmacy, University of Salerno, via Giovanni Paolo II, 132, Fisciano 84084, Italy. Department of Organic Chemistry, Faculty of Chemistry and Technology, University of Split, Rudera Boskovica 35, Split 21000, Croatia. Department of Food Technology and Biotechnology, Faculty of Chemistry and Technology, University of Split, Rudera Boskovica 35, Split 21000, Croatia. Department of Pharmacy, University of Salerno, via Giovanni Paolo II, 132, Fisciano 84084, Italy; Department of Life and Environmental Sciences, University of Cagliari, Via Ospedale, 72, Cagliari 09124, Italy. Department of Life and Environmental Sciences, University of Cagliari, Via Ospedale, 72, Cagliari 09124, Italy. Electronic address: tuberoso@unica.it" |
| DOI: | 10.1016/j.foodres.2018.11.016 |
| ISSN/ISBN: | 1873-7145 (Electronic) 0963-9969 (Linking) |
| Abstract: | "Extracts obtained from Pompia intrea (PI), a traditional candied fruit whose main ingredient is the pompia fruit (Citrus monstruosa L.) were evaluated for the first time. Volatile compounds were evaluated by headspace solid-phase microextraction (HS-SPME) followed by GC-FID/MS analyses. Polar compounds were identified by high-performance liquid chromatography coupled with electrospray mass spectrometry LC-ESI-Orbitrap-MS/MS and quantified by liquid chromatography coupled with ultraviolet/visible detection (LC-DAD). The antioxidant activity of these extracts was tested using the FRAP, CUPRAC, ABTS(*+) and DPPH(?╖+) assays. Moreover, their ability to protect intestinal cells against lipid peroxidation was studied. The HS-SPME GC-FID/MS confirmed the presence of typical molecules originating from the fruit (mainly terpenes, but particularly limonene). The LC-DAD and LC-ESI-(HR)MS(n) profiles showed high levels of neohesperidin (45.7?ª++/-?ª+11.1?ª+mg/L) and 5-(hydroxymethyl)furfural (40.8?ª++/-?ª+23.5?ª+mg/L). The results showed that the PI extracts contained high levels of total phenols and exhibited considerable antioxidant activity, which was significantly correlated to the presence of specific compounds such as neoeriocitrin and neohesperidin. Furthermore, pretreatments with different concentrations of PI extracts preserved enterocytes from oxidative damage by scavenging reactive oxygen species, thus counteracting lipid peroxidation. This study suggests that consumption of PI could provide intake of compounds with ascertained biological activity" |
| Keywords: | "Caco-2 Cells Candy/*analysis Cell Survival/drug effects Chromatography, High Pressure Liquid Citrus/*chemistry Fruit/*chemistry Humans Plant Extracts/*chemistry/toxicity Polyphenols/analysis Solid Phase Microextraction Tandem Mass Spectrometry Terpenes/an;" |
| Notes: | "MedlineDeiana, Monica Montoro, Paola Jerkovic, Igor Atzeri, Angela Marijanovic, Zvonimir Serreli, Gabriele Piacente, Sonia Tuberoso, Carlo Ignazio Giovanni eng Research Support, Non-U.S. Gov't Canada 2019/04/20 Food Res Int. 2019 Jun; 120:620-630. doi: 10.1016/j.foodres.2018.11.016. Epub 2018 Nov 9" |
