| Title: | Real-time measurements of product compounds formed through the reaction of ozone with breath exhaled VOCs |
| Author(s): | Xu X; Pang H; Liu C; Wang K; Loisel G; Li L; Gligorovski S; Li X; |
| Address: | "Institute of Mass Spectrometry and Atmospheric Environment, Jinan University, Guangzhou 510632, China. tamylee@jnu.edu.cn. Guangdong Provincial Engineering Research Center for On-line Source Apportionment System of Air Pollution, Guangzhou, 510632, China. Guangdong-Hongkong-Macau Joint Laboratory of Collaborative Innovation for Environmental Quality, Guangzhou, 510632, China. State Key Laboratory of Organic Geochemistry, Guangdong Provincial Key Laboratory of Environmental Protection and Resources Utilization, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China. gligorovski@gig.ac.cn. Guangdong-Hong Kong-Macao Joint Laboratory for Environmental Pollution and Control, Guangzhou Institute of Geochemistry, Chinese Academy of Science, Guangzhou 510640, China. Chinese Academy of Science, Center for Excellence in Deep Earth Science, Guangzhou, 510640, China" |
| Journal Title: | Environ Sci Process Impacts |
| ISSN/ISBN: | 2050-7895 (Electronic) 2050-7887 (Linking) |
| Abstract: | "Human presence can affect indoor air quality because of secondary organic compounds formed upon reactions between gaseous oxidant species, e.g., ozone (O(3)), hydroxyl radicals (OH), and chemical compounds from skin, exhaled breath, hair and clothes. We assess the gas-phase product compounds generated by reactions of gaseous O(3) with volatile organic compounds (VOCs) from exhaled human breath by real time analysis using a high-resolution quadrupole-orbitrap mass spectrometer (HRMS) coupled to a secondary electrospray ionization (SESI) source. Based on the product compounds identified we propose a reaction mechanism initiated by O(3) oxidation of the most common breath constituents, isoprene, alpha-terpinene and ammonia (NH(3)). The reaction of O(3) with isoprene and alpha-terpinene generates ketones and aldehydes such as 3,4-dihydroxy-2-butanone, methyl vinyl ketone, 3-carbonyl butyraldehyde, formaldehyde and toxic compounds such as 3-methyl furan. Formation of compounds with reduced nitrogen containing functional groups such as amines, imines and imides is highly plausible through NH(3) initiated cleavage of the C-O bond. The detected gas-phase product compounds suggest that human breath can additionally affect indoor air quality through the formation of harmful secondary products and future epidemiological studies should evaluate the potential health effects of these compounds" |
| Keywords: | Humans *Ozone/chemistry *Volatile Organic Compounds/analysis Hemiterpenes *Air Pollutants/analysis; |
| Notes: | "MedlineXu, Xin Pang, Hongwei Liu, Chao Wang, Kangyi Loisel, Gwendal Li, Lei Gligorovski, Sasho Li, Xue eng England 2022/12/07 Environ Sci Process Impacts. 2022 Dec 14; 24(12):2237-2248. doi: 10.1039/d2em00339b" |
