| Title: | Symbioses of Cyanobacteria in Marine Environments: Ecological Insights and Biotechnological Perspectives |
| Author(s): | Mutalipassi M; Riccio G; Mazzella V; Galasso C; Somma E; Chiarore A; de Pascale D; Zupo V; |
| Address: | "Department of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, Italy. Department of Integrated Marine Ecology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, Italy. Department of Life Sciences, University of Trieste, Via Licio Giorgieri, 34127 Trieste, Italy. Department of Marine Biotechnology, Ischia Marine Centre, Stazione Zoologica Anton Dohrn, Punta San Pietro, 80077 Naples, Italy. Department of Biology, University of Naples Federico II, Via Cinthia, 80126 Naples, Italy" |
| ISSN/ISBN: | 1660-3397 (Electronic) 1660-3397 (Linking) |
| Abstract: | "Cyanobacteria are a diversified phylum of nitrogen-fixing, photo-oxygenic bacteria able to colonize a wide array of environments. In addition to their fundamental role as diazotrophs, they produce a plethora of bioactive molecules, often as secondary metabolites, exhibiting various biological and ecological functions to be further investigated. Among all the identified species, cyanobacteria are capable to embrace symbiotic relationships in marine environments with organisms such as protozoans, macroalgae, seagrasses, and sponges, up to ascidians and other invertebrates. These symbioses have been demonstrated to dramatically change the cyanobacteria physiology, inducing the production of usually unexpressed bioactive molecules. Indeed, metabolic changes in cyanobacteria engaged in a symbiotic relationship are triggered by an exchange of infochemicals and activate silenced pathways. Drug discovery studies demonstrated that those molecules have interesting biotechnological perspectives. In this review, we explore the cyanobacterial symbioses in marine environments, considering them not only as diazotrophs but taking into consideration exchanges of infochemicals as well and emphasizing both the chemical ecology of relationship and the candidate biotechnological value for pharmaceutical and nutraceutical applications" |
| Keywords: | "Animals Aquatic Organisms/*microbiology *Bioprospecting Cyanobacteria/*metabolism *Dietary Supplements *Drug Discovery *Ecosystem Evolution, Molecular Humans Pharmaceutical Preparations/*isolation & purification Secondary Metabolism Symbiosis animal inter;" |
| Notes: | "MedlineMutalipassi, Mirko Riccio, Gennaro Mazzella, Valerio Galasso, Christian Somma, Emanuele Chiarore, Antonia de Pascale, Donatella Zupo, Valerio eng PG/2018/0494374/Antitumor Drugs and Vaccines from the Sea (ADViSE) 804 project/ Review Switzerland 2021/05/01 Mar Drugs. 2021 Apr 16; 19(4):227. doi: 10.3390/md19040227" |
