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FEMS Yeast Res

Title:		The pheromone response pathway of Kluyveromyces lactis
Author(s):		Coria R; Kawasaki L; Torres-Quiroz F; Ongay-Larios L; Sanchez-Paredes E; Velazquez-Zavala N; Navarro-Olmos R; Rodriguez-Gonzalez M; Aguilar-Corachan R; Coello G;
Address:		"Departamento de Genetica Molecular, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico, DF, Mexico. rcoria@ifc.unam.mx"
Journal Title:		FEMS Yeast Res
Year:		2006
Volume:		6
Issue:		3
Page Number:		336 - 344
DOI:		10.1111/j.1567-1364.2005.00022.x
ISSN/ISBN:		1567-1356 (Print) 1567-1356 (Linking)
Abstract:		"The mating pheromone response pathway in Saccharomyces cerevisiae is one of the best understood signalling pathways in eukaryotes. Comparison of this system with pathways in other fungal species has generated surprises and insights. Cloning and targetted disruption of genes encoding components of the pheromone response pathway has allowed the attribution of specific functions to these signal transduction components. In this review we describe current knowledge of the Kluyveromyces lactis mating system, and compare it with the well-understood S. cerevisiae pathway, emphasizing the similarities and differences in the heterotrimeric G protein activity. This mating pathway is controlled positively by both the Galpha and the Gbeta subunits of the heterotrimeric G protein"
Keywords:		"Heterotrimeric GTP-Binding Proteins/genetics/physiology Kluyveromyces/genetics/*physiology Pheromones/genetics/*physiology Receptors, Pheromone/physiology Response Elements Saccharomyces cerevisiae/genetics/physiology *Signal Transduction/genetics;"
Notes:		"MedlineCoria, Roberto Kawasaki, Laura Torres-Quiroz, Francisco Ongay-Larios, Laura Sanchez-Paredes, Edith Velazquez-Zavala, Nancy Navarro-Olmos, Rocio Rodriguez-Gonzalez, Miriam Aguilar-Corachan, Rodrigo Coello, Gerardo eng Comparative Study Research Support, Non-U.S. Gov't Review England 2006/04/25 FEMS Yeast Res. 2006 May; 6(3):336-44. doi: 10.1111/j.1567-1364.2005.00022.x"