| Title: | Cross-generation pheromonal communication drives Drosophila oviposition site choice |
| Author(s): | Zhang L; Sun H; Grosse-Wilde E; Zhang L; Hansson BS; Dweck HKM; |
| Address: | "College of Grassland Science and Technology, China Agricultural University, Yuanmingyuan West Rd. 2, Beijing 100193, China; Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Hans-Knoll-Str. 8, 07745 Jena, Germany. Electronic address: lwzhang@cau.edu.cn. College of Grassland Science and Technology, China Agricultural University, Yuanmingyuan West Rd. 2, Beijing 100193, China. Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Hans-Knoll-Str. 8, 07745 Jena, Germany. Institute of Plant Protection, Shandong Academy of Agricultural Sciences, Gongye North Rd. 202, Jinan 250100, China" |
| DOI: | 10.1016/j.cub.2023.03.090 |
| ISSN/ISBN: | 1879-0445 (Electronic) 0960-9822 (Linking) |
| Abstract: | "In a heterogeneous and changing environment, oviposition site selection strongly affects the survival and fitness of the offspring.(1)(,)(2) Similarly, competition between larvae affects their prospects.(3) However, little is known about the involvement of pheromones in regulating these processes.(4)(,)(5)(,)(6)(,)(7)(,)(8) Here, we show that mated females of Drosophila melanogaster prefer to lay eggs on substrates containing extracts of conspecific larvae. After analyzing these extracts chemically, we test each compound in an oviposition assay and find that mated females display a dose-dependent preference to lay eggs on substrates spiked with (Z)-9-octadecenoic acid ethyl ester (OE). This egg-laying preference relies on gustatory receptor Gr32a and tarsal sensory neurons expressing this receptor. The concentration of OE also regulates larval place choice in a dose-dependent manner. Physiologically, OE activates female tarsal Gr32a(+) neurons. In conclusion, our results reveal a cross-generation communication strategy essential for oviposition site selection and regulation of larval density" |
| Keywords: | Animals Female *Drosophila Drosophila melanogaster/physiology Oviposition/physiology Pheromones *Drosophila Proteins/physiology Larva/physiology Drosophila Gr32a Oe gustation larval pheromone oviposition site choice; |
| Notes: | "MedlineZhang, Liwei Sun, Huiwen Grosse-Wilde, Ewald Zhang, Long Hansson, Bill S Dweck, Hany K M eng Research Support, Non-U.S. Gov't England 2023/04/26 Curr Biol. 2023 May 22; 33(10):2095-2103.e3. doi: 10.1016/j.cub.2023.03.090. Epub 2023 Apr 24" |
