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J Occup Environ Hyg

Title:		Effectiveness of personal protective equipment: relevance of dermal and inhalation exposure to chlorpyrifos among pest control operators
Author(s):		van der Jagt K; Tielemans E; Links I; Brouwer D; van Hemmen J;
Address:		"Department of Chemical Exposure Assessment, TNO Chemistry, Zeist, The Netherlands"
Journal Title:		J Occup Environ Hyg
Year:		2004
Volume:		1
Issue:		6
Page Number:		355 - 362
DOI:		10.1080/15459620490449710
ISSN/ISBN:		1545-9624 (Print) 1545-9624 (Linking)
Abstract:		"This study assessed the effectiveness of a custom fit personal protective equipment (PPE) program aimed at reducing occupational exposure to pesticides. The intervention study was carried out on 15 pest control operators (PCOs) during mixing/loading and application of chlorpyrifos. Each worker was measured twice; first while the worker used PPE as normal (baseline measurement), and second after making some adjustments to the PPE (postintervention measurement). The applied intervention consisted of a tight-fitting, full-face respirator, fit-testing, long gloves, chemical-proof boots, a Tyvek hood, and an instruction video that was shown prior to putting on the PPE. A comprehensive evaluation program was used for the within-subject comparisons, including assessment of potential dermal exposure, actual dermal exposure, inhalation exposure, and internal dose as measured by the urinary metabolite 3,5,6-trichloro-2-pyridinol (TCP). The PPE program resulted in a significant increase in fit factors from a mean of 670 to 132,000. Actual dermal exposure levels decreased on average by fourfold after implementation of the PPE program (baseline AM = 132.1 microg; postintervention AM = 32.6 microg). The TCP levels in urine collected 24-32 hours after spray activities were lower in the postintervention data set (AM = 21.2 microg TCP/g creatinine vs. AM = 13.9 microg TCP/g creatinine). However, it is impossible to attribute these differences totally to the PPE program since workers had significant and varying urinary TCP levels before onset of spraying activities. Linear regression models showed that dermal exposure was only a predictive parameter for TCP levels in urine in the baseline data set. Although the results should be interpreted cautiously this study suggests a protective effect of the evaluated PPE program"
Keywords:		"Administration, Cutaneous Chlorpyrifos/*analysis Equipment Design Humans Inhalation Exposure/*prevention & control *Insect Control Insecticides/*analysis Occupational Exposure/*prevention & control *Protective Devices;"
Notes:		"Medlinevan der Jagt, Katinka Tielemans, Erik Links, Ingrid Brouwer, Dick van Hemmen, Joop eng Research Support, Non-U.S. Gov't England 2004/07/09 J Occup Environ Hyg. 2004 Jun; 1(6):355-62. doi: 10.1080/15459620490449710"