| Title: | Comparison of Membrane Inlet and Capillary Introduction Miniature Mass Spectrometry for Liquid Analysis |
| Author(s): | Shi W; Lu X; Zhang J; Zhao J; Yang L; Yu Q; Wang X; |
| Address: | "Division of Advanced Manufacturing, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. shiwenyanu@163.com. State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Beijing 100084, China. shiwenyanu@163.com. Division of Advanced Manufacturing, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. xqlu@tsinghua.info. Guangdong Province Engineering Research, Center for Urban Water Recycling and Environmental Safety, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. xqlu@tsinghua.info. Division of Advanced Manufacturing, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. zhangjb16@mails.tsinghua.edu.cn. Division of Advanced Manufacturing, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. jh-zhao17@mails.tsinghua.edu.cn. Hebei Province Key Lab of Measurement Technology and Instrumentation, Yanshan University, Qinhuangdao 066004, China. lily@ysu.net.cn. Division of Advanced Manufacturing, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. yu.quan@sz.tsinghua.edu.cn. Division of Advanced Manufacturing, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. xhwang@tsinghua.edu.cn. State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Beijing 100084, China. xhwang@tsinghua.edu.cn" |
| ISSN/ISBN: | 2073-4360 (Electronic) 2073-4360 (Linking) |
| Abstract: | "Membrane inlet mass spectrometry (MIMS) is commonly used for detecting the components in liquid samples. When a liquid sample flows through a membrane, certain analytes will permeate into the vacuum chamber of a mass spectrometer from the solution. The properties of the membrane directly determine the substances that can be detected by MIMS. A capillary introduction (CI) method we previously proposed can also be used to analyze gas and volatile organic compounds (VOCs) dissolved in liquids. When CI analysis is carried out, the sample is drawn into the mass spectrometer with no species discrimination. The performance of these two injection methods was compared in this study, and similar response time and limit of detection (LOD) can be acquired. Specifically, MIMS can provide better detection sensitivity for most inorganic gases and volatile organic compounds. In contrast, capillary introduction shows wider compatibility on analyte types and quantitative range, and it requires less sample consumption. As the two injection methods have comparable characteristics and can be coupled with a miniature mass spectrometer, factors such as cost, pollution, device size, and sample consumption should be comprehensively considered when choosing a satisfactory injection method in practical applications" |
| Keywords: | capillary introduction mass spectrometry membrane inlet performance comparison; |
| Notes: | "PubMed-not-MEDLINEShi, Wenyan Lu, Xinqiong Zhang, Jinbo Zhao, Jianhong Yang, Lili Yu, Quan Wang, Xiaohao eng 21775085/National Natural Science Foundation of China/ JCYJ20160428182352200/Shenzhen Fundamental Research Program/ 201501B053/Key Technology R&D Program of Qinhuangdao/ Switzerland 2019/04/10 Polymers (Basel). 2019 Mar 26; 11(3):567. doi: 10.3390/polym11030567" |
