| Title: | Hormonal regulation of metamorphosis and reproduction in ticks |
| Author(s): | Roe RM; Donohue KV; Khalil SM; Sonenshine DE; |
| Address: | "Department of Entomology, North Carolina State University, Raleigh, North Carolina 27695-7647, USA. Michael_Roe@ncsu.edu" |
| ISSN/ISBN: | 1093-9946 (Print) 1093-4715 (Linking) |
| Abstract: | "The presence of a 'status quo' hormone like JH has not been found in ticks. The most advanced understanding of tick endocrinology is associated with female reproduction, where the sequence of the first messages for storage proteins (vitellogenin (Vg) and carrier protein), the Vg receptor, and male peptidic pheromones were recently reported. The current consensus model suggests that ecdysteroids from the epidermis regulated by a putative peptidic ecdysiotrophic hormone from the synganlion initiates the expression of the Vg messages in fat body and midgut. Vg protein, secreted into the hemolymph, requires an ovary Vg receptor to be absorbed by oocytes. Male pheromones transferred into the female genital tract during mating initiate blood feeding to repletion and vitellogenesis. The work so far on tick endocrinology is limited by the paucity of identified hormones and the small number of studies on a few tick models. The role of storage proteins in the evolution of hematophagy is discussed" |
| Keywords: | "Animals Female Homeostasis Insect Hormones/*physiology Insect Proteins/genetics/physiology Male Metamorphosis, Biological/*physiology Molecular Biology/methods Pheromones/physiology Reproduction Sexual Behavior, Animal/physiology Ticks/*physiology Vitello;" |
| Notes: | "MedlineRoe, R Michael Donohue, Kevin V Khalil, Sayed M S Sonenshine, Daniel E eng Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review 2008/05/30 Front Biosci. 2008 May 1; 13:7250-68. doi: 10.2741/3226" |
