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FEBS Lett

Title:		"Isolation and structure of the Streptococcus faecalis sex pheromone, cAM373"
Author(s):		Mori M; Tanaka H; Sakagami Y; Isogai A; Fujino M; Kitada C; White BA; An FY; Clewell DB; Suzuki A;
Address:
Journal Title:		FEBS Lett
Year:		1986
Volume:		206
Issue:		1
Page Number:		69 - 72
DOI:		10.1016/0014-5793(86)81342-4
ISSN/ISBN:		0014-5793 (Print) 0014-5793 (Linking)
Abstract:		"The Streptococcus faecalis sex pheromone, cAM373, which induces a mating response of donor cells harboring plasmid pAM373 and is also produced by Staphylococcus aureus, was isolated and its structure determined. Supernatant from an overnight culture of a recipient strain was subjected to successive purification procedures, and 4.4 micrograms cAM373 was obtained. The isolated pheromone showed activity at a concentration as low as 5 X 10(-11) M. Sequence analysis indicated that cAM373 was a heptapeptide, H-Ala-Ile-Phe-Ile-Leu-Ala-Ser-OH, and that its Mr was 733. A synthetic replicate of the peptide showed the same biological activity and chromatographic behavior as the native cAM373"
Keywords:		Amino Acid Sequence Enterococcus faecalis/*analysis Oligopeptides/*isolation & purification Pheromones;
Notes:		"MedlineMori, M Tanaka, H Sakagami, Y Isogai, A Fujino, M Kitada, C White, B A An, F Y Clewell, D B Suzuki, A eng Research Support, Non-U.S. Gov't England 1986/09/29 FEBS Lett. 1986 Sep 29; 206(1):69-72. doi: 10.1016/0014-5793(86)81342-4"