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FEMS Microbiol Lett

Title:		Inhibitory effects of nucleoside 5'-alkylphosphates on sexual agglutination in Saccharomyces cerevisiae
Author(s):		Machida K; Tanaka T; Shibata K; Taniguchi M;
Address:		"Faculty of Science, Osaka City University, Japan"
Journal Title:		FEMS Microbiol Lett
Year:		1997
Volume:		147
Issue:		1
Page Number:		17 - 22
DOI:		10.1111/j.1574-6968.1997.tb10214.x
ISSN/ISBN:		0378-1097 (Print) 0378-1097 (Linking)
Abstract:		"Among various nucleoside 5'-alkylphosphates, uridine 5'-hexadecylphosphate (UMPC16) and adenosine 5'-hexadecylphosphate (AMPC16) inhibited the sexual agglutination between a and alpha haploid cells of Saccharomyces cerevisiae. The effect of AMPC16 accompanied severe growth inhibition of the yeast cells but it was not observed with UMPC16. Sexual agglutination was not inhibited by the presence of UMPC16 or AMPC16 when the yeast cells had been pretreated with the mating pheromone. UMPC16 was characterized as a specific inhibitor of sexual agglutination without direct influence on the agglutinin function, being distinguishable from any of those ever known"
Keywords:		"Adenine Nucleotides/chemical synthesis/*pharmacology Cell Division/drug effects Mating Factor Peptides/pharmacology Pheromones/pharmacology Reproduction, Asexual/*drug effects Saccharomyces cerevisiae/drug effects/*physiology Uracil Nucleotides/chemical s;"
Notes:		"MedlineMachida, K Tanaka, T Shibata, K Taniguchi, M eng England 1997/02/01 FEMS Microbiol Lett. 1997 Feb 1; 147(1):17-22. doi: 10.1111/j.1574-6968.1997.tb10214.x"