| Title: | Autocrine response of Schizosaccharomyces pombe haploid cells to mating pheromones |
| Author(s): | Kitamura K; Nakamura T; Miki F; Shimoda C; |
| Address: | "Department of Biology, Faculty of Science, Osaka City University, Japan" |
| DOI: | 10.1111/j.1574-6968.1996.tb08459.x |
| ISSN/ISBN: | 0378-1097 (Print) 0378-1097 (Linking) |
| Abstract: | "The mating response of the fission yeast Schizosaccharomyces pombe is mediated by mating pheromones, M-factor and P-factor, produced by h- and h+ cells, respectively. When the M-factor receptor (Map3) was ectopically expressed in h- cells lacking the P-factor receptor (Mam2), they acquired mating competence in response to M-factor which they secreted. The autocrine response to P-factor in h- cells was so weak that mating competence was not acquired, although expression of the pheromone-responsive gene matl-Pm was detected. These observations support the notion that the intensity of cellular response to mating phermones is different between h- and h+ cells, although downstream pathways of the pheromone receptors are shared by the two mating types" |
| Keywords: | "Cloning, Molecular DNA-Binding Proteins Gene Expression Genes, Fungal Intercellular Signaling Peptides and Proteins Meiosis/genetics/physiology Peptides/genetics/*physiology Pheromones/genetics/*physiology Restriction Mapping Schizosaccharomyces/genetics/;" |
| Notes: | "MedlineKitamura, K Nakamura, T Miki, F Shimoda, C eng Research Support, Non-U.S. Gov't England 1996/09/15 FEMS Microbiol Lett. 1996 Sep 15; 143(1):41-5. doi: 10.1111/j.1574-6968.1996.tb08459.x" |
