| Title: | Molecular cloning of newt sex pheromone precursor cDNAs: evidence for the existence of species-specific forms of pheromones |
| Author(s): | Iwata T; Umezawa K; Toyoda F; Takahashi N; Matsukawa H; Yamamoto K; Miura S; Hayashi H; Kikuyama S; |
| Address: | "Department of Biology, School of Education, Waseda University, Nishi-waseda 1-6-1, Shinjuku-ku, Tokyo, Japan" |
| DOI: | 10.1016/s0014-5793(99)01062-5 |
| ISSN/ISBN: | 0014-5793 (Print) 0014-5793 (Linking) |
| Abstract: | "Cloning of cDNA encoding a decapeptide pheromone (sodefrin) that attracts conspecific female newts was attempted. A cDNA clone encoding a protein consisting of 189 amino acid residues including a sodefrin sequence was isolated from a Cynops pyrrhogaster abdominal gland cDNA library. Likewise, a cDNA clone encoding a molecule comparable to the sodefrin precursor was obtained from a Cynops ensicauda abdominal gland cDNA library. This clone encoded a precursor protein of 192 amino acid residues, including a sodefrin-like peptide sequence with substitutions of two amino acid residues. This is the first report of a peptide pheromone precursor in vertebrates" |
| Keywords: | "Abdomen/anatomy & histology/physiology Amino Acid Sequence Animals Base Sequence Blotting, Northern Cloning, Molecular DNA, Complementary/classification Female Male Molecular Sequence Data Oligopeptides/genetics/*metabolism/pharmacology Protein Precursors;" |
| Notes: | "MedlineIwata, T Umezawa, K Toyoda, F Takahashi, N Matsukawa, H Yamamoto, K Miura, S Hayashi, H Kikuyama, S eng Research Support, Non-U.S. Gov't England 1999/09/03 FEBS Lett. 1999 Sep 3; 457(3):400-4. doi: 10.1016/s0014-5793(99)01062-5" |
