| Title: | "Impact of differential occupational LPG exposure on cardiopulmonary indices, liver function, and oxidative stress in Northwestern city of Nigeria" |
| Author(s): | Ismail AU; Ibrahim SA; Gambo MD; Muhammad RF; Badamasi MM; Sulaiman I; |
| Address: | "Department of Human Physiology, Faculty of Basic Health Sciences, Al - Istiqama University, Nigeria; Department of Human Physiology, Faculty of Basic Medical Sciences, Bayero University, Nigeria. Department of Human Physiology, Faculty of Basic Medical Sciences, Bayero University, Nigeria. Department of Human Physiology, Faculty of Basic Medical Sciences, Yusuf Maitama Sule University Kano, Nigeria. Department of Geography, Center for Dryland Agriculture (CDA), Bayero University, Nigeria. Department of Human Physiology, Faculty of Basic Medical Sciences, Bayero University, Nigeria; Faculty of Medical Sciences, The University of the West Indies, Cave Hill, Barbados. Electronic address: ibrahim.sulaiman@cavehill.uwi.edu" |
| DOI: | 10.1016/j.scitotenv.2022.160881 |
| ISSN/ISBN: | 1879-1026 (Electronic) 0048-9697 (Linking) |
| Abstract: | "Exposure to hydrocarbon products has been associated with numerous health risks and toxicities. Outdoor or indoor occupational exposure to highly volatile and lipid-soluble hydrocarbons has been linked to impairment of respiratory, cardiovascular, and liver functions. This study is aimed at determining the potential impact of occupational exposure to liquefied petroleum gas (LPG) in varying work environments. Respiratory symptoms, oxidative stress, cardio-pulmonary, and liver function parameters were assessed among LPG workers in the Kano metropolis, Nigeria. Study subjects were recruited from LPG filling stations and street LPG retail shops. Results of the study showed that the forced vital capacity (FVC) of LPG station workers was significantly lower (2.81 L/min; H = 22.473, p < 0.001) relative to the values recorded among LPG retail shop workers and the controls (3.54 L/min and 4.24 L/min respectively). A similar reduction was seen in the forced expiratory volume in the first second (FEV(1)) and the forced expiratory flow in 25-75 % of forced vital capacity (FEF(25)(-)(75)) obtained from the filling station workers (H = 32.722, p < 0.001 & H = 15.655, p <0.001 respectively). Furthermore, exposure to non-combusted LPG increased systolic blood pressure, mean arterial pressure, and serum liver enzymes. Findings from this study revealed that despite the high amount of coarse particulate matter in LPG retail shops, the filling station workers are more susceptible to the impairment of lung function possibly due to the high quantity of total volatile organic compounds (TVOCs) in the filling station environment" |
| Keywords: | Humans Nigeria *Occupational Exposure/adverse effects Forced Expiratory Volume Vital Capacity *Petroleum Oxidative Stress Liver Liver enzymes Occupational hazard Particulate matter Spirometry Volatile organic compounds; |
| Notes: | "MedlineIsmail, Abubakar Usman Ibrahim, Salisu Ahmed Gambo, Mahdi Dissi Muhammad, Ramlah Farouq Badamasi, Murtala Muhammad Sulaiman, Ibrahim eng Netherlands 2022/12/16 Sci Total Environ. 2023 Mar 1; 862:160881. doi: 10.1016/j.scitotenv.2022.160881. Epub 2022 Dec 12" |
