| Title: | "Cross-Reactive, Self-Encoded Polymer Film Arrays for Sensor Applications" |
| Author(s): | Fitzgerald JE; Fenniri H; |
| Address: | "Department of Bioengineering and Department on Chemical Engineering, Northeastern University, Boston, MA, USA. Departments of Chemical Engineering, Bioengineering, Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA. h.fenniri@northeastern.edu" |
| DOI: | 10.1007/978-1-4939-9616-2_1 |
| ISSN/ISBN: | 1940-6029 (Electronic) 1064-3745 (Linking) |
| Abstract: | "The development of chemical sensors continues to be an active area of research, especially the development of a practical electronic nose. Here, we present a spectroscopic chemical sensor based on an array of 64 self-encoded polymer films deposited on a microfabricated silicon substrate. The polymer arrays were analyzed by FTIR and Raman spectroscopy before and after exposure to a series of organic volatiles to monitor changes in their vibrational fingerprints. We show here that the spectroscopic changes of self-encoded polymer films can be used to distinguish between volatile organic analytes. Changes induced in the sensor arrays by the analyte vapor were denoted by a spectroscopic response of the self-encoded polymer sensors and transformed into a response pattern by multivariate data analysis using partial least squares regression. The results indicated that the polymer sensors provide a unique and reproducible pattern for each analyte vapor and can potentially be used in the fabrication of a novel electronic nose device" |
| Keywords: | Biomimetic Materials/*chemistry Chemical Engineering/*methods *Electronic Nose High-Throughput Screening Assays/instrumentation Microtechnology/methods Polymers/*chemistry Reproducibility of Results Silicon/chemistry Volatile Organic Compounds/analysis Ba; |
| Notes: | "MedlineFitzgerald, Jessica E Fenniri, Hicham eng 2019/07/17 Methods Mol Biol. 2019; 2027:1-13. doi: 10.1007/978-1-4939-9616-2_1" |
