| Title: | Ultrasensitive Sensing of Volatile Organic Compounds Using a Cu-Doped SnO(2) -NiO p-n Heterostructure That Shows Significant Raman Enhancement* |
| Author(s): | Zhou Y; Gu Q; Qiu T; He X; Chen J; Qi R; Huang R; Zheng T; Tian Y; |
| Address: | "State Key Laboratory of Precision Spectroscopy, East China Normal University, Dongchuan Road 500, Shanghai, 200241, China. Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, Dongchuan Road 500, Shanghai, 200241, China. Oncology department, Jiangsu Province Hospital, Guangzhou Road 300, Nanjing, 210000, China. Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Dongchuan Road 500, Shanghai, 200241, China. Key laboratory of Polar Materials and Devices (MOE), Department of Optoelectronics, East China Normal University, Dongchuan Road 500, Shanghai, 200241, China" |
| ISSN/ISBN: | 1521-3773 (Electronic) 1433-7851 (Linking) |
| Abstract: | "Surface enhanced Raman scattering (SERS) based on chemical mechanism (CM) attracts tremendous attention for great selectivity and stability. However, low enhancement factor (EF) limits its practical applications for trace detection. Here, a novel sponge-like Cu-doping SnO(2) -NiO p-n semiconductor heterostructure (SnO(2) -NiO(x) /Cu), was first created as a CM-based SERS substrate with a significant EF of 1.46x10(10) . This remarkable EF was mainly attributed to the enhanced charge-separation efficacy of p-n heterojunction and charge transfer resonance resulted from Cu doping. Moreover, the porous structure enriched the probe molecules, resulting in further SERS signals magnification. By immobilizing CuPc as an inner-reference element, SnO(2) -NiO(x) /Cu was developed as a SERS nose for selective recognition of multiple lung cancer related VOCs down to ppb level. The information of VOCs was recorded in a barcode, demonstrating practical potential of a desktop SERS device for biomarker screening" |
| Keywords: | "Copper/*chemistry Nickel/*chemistry Semiconductors Spectrum Analysis, Raman Tin Compounds/*chemistry Volatile Organic Compounds/*analysis VOC sensing p-n heterojunction surface enhanced Raman scattering;" |
| Notes: | "MedlineZhou, Yan Gu, Qingyi Qiu, Tianzhu He, Xiao Chen, Jinquan Qi, Ruijuan Huang, Rong Zheng, Tingting Tian, Yang eng 21827814/National Natural Science Foundation of China/ 21974049/National Natural Science Foundation of China/ 201701070005E00020/Innovation Program of Shanghai Municipal Education Commission/ 20QA1403300/Shanghai Rising-Star Program/ Research Support, Non-U.S. Gov't Germany 2021/10/07 Angew Chem Int Ed Engl. 2021 Dec 6; 60(50):26260-26267. doi: 10.1002/anie.202112367. Epub 2021 Nov 8" |
