| Title: | On-line coupling of fizzy extraction with gas chromatography |
| Address: | "Department of Chemistry, National Tsing Hua University, 101 Section 2, Kuang-Fu Road, Hsinchu, 30013, Taiwan. Department of Applied Chemistry, National Chiao Tung University, 1001 University Road, Hsinchu, 300, Taiwan. Department of Chemistry, National Tsing Hua University, 101 Section 2, Kuang-Fu Road, Hsinchu, 30013, Taiwan. urban@mx.nthu.edu.tw. Frontier Research Center on Fundamental and Applied Sciences of Matters, National Tsing Hua University, 101 Section 2, Kuang-Fu Road, Hsinchu, 30013, Taiwan. urban@mx.nthu.edu.tw" |
| DOI: | 10.1007/s00216-019-01755-9 |
| ISSN/ISBN: | 1618-2650 (Electronic) 1618-2642 (Linking) |
| Abstract: | "Fizzy extraction (FE) is carried out by first dissolving a carrier gas (typically, carbon dioxide) in a liquid sample at a moderate pressure (typically, 150 kPa) and then rapidly depressurizing the sample. The depressurization leads to instant release of numerous microbubbles in the liquid matrix. The abruptly released gas extracts the volatile solutes and elutes them toward a detector in a short period of time. Here, we describe on-line coupling of FE with gas chromatography (GC). The two platforms are highly compatible and could be combined following several modifications of the interface and adjustments of the extraction sequence. The analytes are released within a short period of time (1.5 s). Thus, the chromatographic peaks are satisfactorily narrow. There is no need to trap the extracted analytes in a loop or on a sorbent, as it is done in standard headspace and microextraction methods. The approach requires only minor sample pretreatment. The main parameters of the FE-GC-mass spectrometry (MS) method were optimized. The results of FE were compared with those of headspace flushing (scavenging headspace vapors), and the enhancement factors were in the order of ~ 2 to 13 (for various analytes). The limits of detection for some of the tested analytes were lower in the proposed FE-GC-MS method than in FE combined with atmospheric pressure chemical ionization MS. The method was further tested in analyses of selected real samples (apple flavor milk, mixed fruit and vegetable juice drink, mango flavored drink, pineapple green tea, toothpaste, and yogurt). Graphical abstract" |
| Keywords: | Fruit and Vegetable Juices/*analysis Gas Chromatography-Mass Spectrometry/*methods Gases/chemistry Limit of Detection *Phase Transition Reproducibility of Results Volatile Organic Compounds/*analysis Extraction Gas chromatography Sample preparation Volati; |
| Notes: | "MedlineYang, Hao-Chun Urban, Pawel L eng 107-3017-F-007-002/Ministry of Science and Technology, Taiwan/ Germany 2019/03/27 Anal Bioanal Chem. 2019 May; 411(12):2511-2520. doi: 10.1007/s00216-019-01755-9. Epub 2019 Mar 26" |
