| Title: | "Synthesis of fluorescent molecular probes specific for the receptor of blepharismone, a mating-inducing pheromone of the ciliate Blepharisma japonicum" |
| Author(s): | Uruma Y; Sugiura M; Harumoto T; Usuki Y; Iio H; |
| Address: | "Department of Material Science, Graduate School of Science, Osaka City University, Osaka 558-8585, Japan" |
| DOI: | 10.1016/j.bmc.2006.12.021 |
| ISSN/ISBN: | 0968-0896 (Print) 0968-0896 (Linking) |
| Abstract: | "Blepharismone (gamone 2) is a mating-inducing pheromone of the ciliate Blepharisma japonicum. N-Pyrenylbutyryl-blepharismone and N-biphenylacetyl-blepharismone, which are fluorescent derivatives of blepharismone, were synthesized as molecular probes for the gamone 2 receptor. Further, we proved that they have inhibitory activities against the blepharismone-induced monotypic pairing of B. japonicum" |
| Keywords: | "Aminophenols Animals Fluorescent Dyes/*chemical synthesis Hydroxybenzoates/*antagonists & inhibitors/chemical synthesis Lactates Protozoan Proteins/antagonists & inhibitors Receptors, Pheromone/analysis/antagonists & inhibitors Sex Attractants/*antagonist;" |
| Notes: | "MedlineUruma, Yoshiyuki Sugiura, Mayumi Harumoto, Terue Usuki, Yoshinosuke Iio, Hideo eng Research Support, Non-U.S. Gov't England 2006/12/27 Bioorg Med Chem. 2007 Feb 15; 15(4):1622-7. doi: 10.1016/j.bmc.2006.12.021. Epub 2006 Dec 14" |
