Title: | Quorum sensing: a population-density component in the determination of bacterial phenotype |
Author(s): | Swift S; Throup JP; Williams P; Salmond GP; Stewart GS; |
Address: | "Department of Applied Biochemistry and Food Science, University of Nottingham, Leicestershire, UK" |
ISSN/ISBN: | 0968-0004 (Print) 0968-0004 (Linking) |
Abstract: | "In bacteria, a network of cellular transduction mechanisms integrate signals from the bacterial environment to control gene expression, and thereby the bacterial phenotype. 'Quorum sensing' describes one such signalling mechanism in response to population density. It relies on the accumulation of small extracellular signalling molecules to modulate the transcription of target operons" |
Keywords: | "Anti-Bacterial Agents/biosynthesis Bacteria/*metabolism Bacterial Proteins/metabolism/pharmacology Cell Division/drug effects Conjugation, Genetic/physiology Enzymes/biosynthesis Gene Expression Regulation, Bacterial/genetics Homoserine/analogs & derivati;" |
Notes: | "MedlineSwift, S Throup, J P Williams, P Salmond, G P Stewart, G S eng Wellcome Trust/United Kingdom Research Support, Non-U.S. Gov't England 1996/06/01 Trends Biochem Sci. 1996 Jun; 21(6):214-9" |