Title: | The Role of Electronic Noses in Phenotyping Patients with Chronic Obstructive Pulmonary Disease |
Author(s): | Scarlata S; Finamore P; Meszaros M; Dragonieri S; Bikov A; |
Address: | "Unit of Internal Medicine, Campus Bio Medico University and Teaching Hospital, 00128 Rome, Italy. Unit of Geriatrics, Campus Bio Medico University and Teaching Hospital, 00128 Rome, Italy. Department of Pulmonology and Sleep Disorders Centre, University Hospital Zurich, 8091 Zurich, Switzerland. Respiratory and Sleep Medicine Unit, Policlinico University Hospital, University of Bari Aldo Moro, 70124 Bari, Italy. Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester M23 9LT, UK. Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester M13 9NT, UK" |
ISSN/ISBN: | 2079-6374 (Electronic) 2079-6374 (Linking) |
Abstract: | "Chronic obstructive pulmonary disease (COPD) is a common progressive disorder of the respiratory system which is currently the third leading cause of death worldwide. Exhaled breath analysis is a non-invasive method to study lung diseases, and electronic noses have been extensively used in breath research. Studies with electronic noses have proved that the pattern of exhaled volatile organic compounds is different in COPD. More recent investigations have reported that electronic noses could potentially distinguish different endotypes (i.e., neutrophilic vs. eosinophilic) and are able to detect microorganisms in the airways responsible for exacerbations. This article will review the published literature on electronic noses and COPD and help in identifying methodological, physiological, and disease-related factors which could affect the results" |
Keywords: | "Breath Tests *Electronic Nose Exhalation Humans Pulmonary Disease, Chronic Obstructive/*diagnosis Volatile Organic Compounds Copd VOCs chronic obstructive pulmonary disease e-nose electronic nose;" |
Notes: | "MedlineScarlata, Simone Finamore, Panaiotis Meszaros, Martina Dragonieri, Silvano Bikov, Andras eng Review Switzerland 2020/11/15 Biosensors (Basel). 2020 Nov 11; 10(11):171. doi: 10.3390/bios10110171" |