Title: | Self-Healable Sensors Based Nanoparticles for Detecting Physiological Markers via Skin and Breath: Toward Disease Prevention via Wearable Devices |
Author(s): | Jin H; Huynh TP; Haick H; |
Address: | "The Faculty of Information Science and Engineering, Ningbo University , Ningbo 315211, P. R. China" |
DOI: | 10.1021/acs.nanolett.6b01066 |
ISSN/ISBN: | 1530-6992 (Electronic) 1530-6984 (Linking) |
Abstract: | "Flexible and wearable electronic sensors are useful for the early diagnosis and monitoring of an individual's health state. Sampling of volatile organic compounds (VOCs) derived from human breath/skin or monitoring abrupt changes in heart-beat/breath rate should allow noninvasive monitoring of disease states at an early stage. Nevertheless, for many reported wearable sensing devices, interaction with the human body leads incidentally to unavoidable scratches and/or mechanical cuts and bring about malfunction of these devices. We now offer proof-of-concept of nanoparticle-based flexible sensor arrays with fascinating self-healing abilities. By integrating a self-healable polymer substrate with 5 kinds of functionalized gold nanoparticle films, a sensor array gives a fast self-healing (<3 h) and attractive healing efficiency in both the substrate and sensing films. The proposed platform was used in sensing pressure variation and 11 kinds of VOCs. The sensor array had satisfactory sensitivity, a low detection limit, and promising discrimination features in monitoring both of VOCs and pressure variation, even after full healing. These results presage a new type of smart sensing device, with a desirable performance in the possible detection and/or clinical application for a number of different purposes" |
Keywords: | Breath Tests/*instrumentation Gold Humans *Metal Nanoparticles Skin/*chemistry Volatile Organic Compounds/*analysis *Wearable Electronic Devices Sensor flexible nanoparticle self-healable volatile organic compound wearable; |
Notes: | "MedlineJin, Han Huynh, Tan-Phat Haick, Hossam eng Research Support, Non-U.S. Gov't 2016/06/22 Nano Lett. 2016 Jul 13; 16(7):4194-202. doi: 10.1021/acs.nanolett.6b01066. Epub 2016 Jun 27" |