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Peptides

Title:		A walk-through of the yeast mating pheromone response pathway
Author(s):		Bardwell L;
Address:		"Department of Developmental and Cell Biology, 2208 Natural Sciences I, University of California, Irvine, CA 92697-2300, USA. bardwell@uci.edu"
Journal Title:		Peptides
Year:		2004
Volume:		25
Issue:		9
Page Number:		1465 - 1476
DOI:		10.1016/j.peptides.2003.10.022
ISSN/ISBN:		0196-9781 (Print) 0196-9781 (Linking)
Abstract:		"The intracellular signal transduction pathway by which the yeast Saccharomyces cerevisiae responds to the presence of peptide mating pheromone in its surroundings is one of the best understood signaling pathways in eukaryotes, yet continues to generate new surprises and insights. In this review, we take a brief walk down the pathway, focusing on how the signal is transmitted from the cell-surface receptor-coupled G protein, via a MAP kinase cascade, to the nucleus"
Keywords:		"Cell Membrane/metabolism GTP-Binding Proteins/chemistry *Genes, Fungal Humans MAP Kinase Kinase Kinases/metabolism MAP Kinase Signaling System/physiology Models, Biological Peptides/chemistry Pheromones/chemistry Protein Binding Protein Structure, Tertiar;"
Notes:		"MedlineBardwell, Lee eng R01 GM060366/GM/NIGMS NIH HHS/ R01 GM060366-04/GM/NIGMS NIH HHS/ GM60366/GM/NIGMS NIH HHS/ GM69013/GM/NIGMS NIH HHS/ Research Support, U.S. Gov't, P.H.S. Review 2004/09/18 Peptides. 2004 Sep; 25(9):1465-76. doi: 10.1016/j.peptides.2003.10.022"