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Plasmid

Title:		"Enterococcus faecalis pheromone-responding plasmid pAD1 gives rise to an aggregation (clumping) response when cells are exposed to subinhibitory concentrations of chloramphenicol, erythromycin, or tetracycline"
Author(s):		Wu K; An FY; Clewell DB;
Address:		"Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, Michigan, 48109, USA"
Journal Title:		Plasmid
Year:		1999
Volume:		41
Issue:		1
Page Number:		82 - 88
DOI:		10.1006/plas.1998.1373
ISSN/ISBN:		0147-619X (Print) 0147-619X (Linking)
Abstract:		"The Enterococcus faecalis conjugative cytolysin plasmid pAD1 encodes a specific aggregation (clumping) response to the peptide sex pheromone cAD1 secreted by plasmid-free strains. Here it is shown that, in the absence of cAD1, exposure of E. faecalis cells harboring pAD1 to subinhibitory concentrations of chloramphenicol, erythromycin, or tetracycline also results in an aggregation response that appears related to a stress-sensitive mechanism associated with a component of the pheromone response"
Keywords:		Anti-Bacterial Agents/*pharmacology Bacterial Outer Membrane Proteins/genetics Bacterial Proteins/genetics Cell Aggregation/drug effects Chloramphenicol/*pharmacology Enterococcus faecalis/drug effects/*genetics Erythromycin/*pharmacology Fimbriae Protein;
Notes:		"MedlineWu, K An, F Y Clewell, D B eng GM33956/GM/NIGMS NIH HHS/ Research Support, U.S. Gov't, P.H.S. 1999/01/15 Plasmid. 1999 Jan; 41(1):82-8. doi: 10.1006/plas.1998.1373"